Genes that are thought to be critical for the survival of organisms or cells are called essential
genes. The prediction of essential genes and their products (essential proteins) is of great …

Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

Information on protein subcellular localization is important to understand the cellular
functions of proteins. Currently, such information is manually curated from the literature …

Increasing evidence has revealed that RNA subcellular localization is a very important
feature for deeply understanding RNA's biological functions after being transported into intra …

Ovarian cancer is the most lethal type of cancer among all frequent gynecologic
malignancies, because most patients present with advanced disease at diagnosis …

Phosphatases are crucially involved in cellular processes by dephosphorylating cellular
components. We describe a structure-based classification scheme for all active human …

The composition of the nucleoplasm determines the behavior of key processes such as
transcription, yet there is still no reliable and quantitative resource of nuclear proteins …

Human protein subcellular localization has an important research value in biological
processes, also in elucidating protein functions and identifying drug targets. Over the past …

Motivation: Subcellular localization is one aspect of protein function. Despite advances in
high-throughput imaging, localization maps remain incomplete. Several methods accurately …

It has become clear in outline though not yet in detail how cellular regulatory and signalling
systems are constructed. The essential machines are protein complexes that effect …