Network-based methods for predicting essential genes or proteins: a survey
Genes that are thought to be critical for the survival of organisms or cells are called essential
genes. The prediction of essential genes and their products (essential proteins) is of great …
genes. The prediction of essential genes and their products (essential proteins) is of great …
Application of machine learning in spatial proteomics
Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …
of proteins, and it has gained extensive attention in recent years, especially the subcellular …
[HTML][HTML] COMPARTMENTS: unification and visualization of protein subcellular localization evidence
Information on protein subcellular localization is important to understand the cellular
functions of proteins. Currently, such information is manually curated from the literature …
functions of proteins. Currently, such information is manually curated from the literature …
RNALocate: a resource for RNA subcellular localizations
T Zhang, P Tan, L Wang, N Jin, Y Li… - Nucleic acids …, 2017 - academic.oup.com
Increasing evidence has revealed that RNA subcellular localization is a very important
feature for deeply understanding RNA's biological functions after being transported into intra …
feature for deeply understanding RNA's biological functions after being transported into intra …
Characterization and proteomic analysis of ovarian cancer-derived exosomes
B Liang, P Peng, S Chen, L Li, M Zhang, D Cao… - Journal of …, 2013 - Elsevier
Ovarian cancer is the most lethal type of cancer among all frequent gynecologic
malignancies, because most patients present with advanced disease at diagnosis …
malignancies, because most patients present with advanced disease at diagnosis …
Elucidating human phosphatase-substrate networks
X Li, M Wilmanns, J Thornton, M Köhn - Science signaling, 2013 - science.org
Phosphatases are crucially involved in cellular processes by dephosphorylating cellular
components. We describe a structure-based classification scheme for all active human …
components. We describe a structure-based classification scheme for all active human …
The nuclear proteome of a vertebrate
The composition of the nucleoplasm determines the behavior of key processes such as
transcription, yet there is still no reliable and quantitative resource of nuclear proteins …
transcription, yet there is still no reliable and quantitative resource of nuclear proteins …
Critical evaluation of web-based prediction tools for human protein subcellular localization
Human protein subcellular localization has an important research value in biological
processes, also in elucidating protein functions and identifying drug targets. Over the past …
processes, also in elucidating protein functions and identifying drug targets. Over the past …
LocTree2 predicts localization for all domains of life
T Goldberg, T Hamp, B Rost - Bioinformatics, 2012 - academic.oup.com
Motivation: Subcellular localization is one aspect of protein function. Despite advances in
high-throughput imaging, localization maps remain incomplete. Several methods accurately …
high-throughput imaging, localization maps remain incomplete. Several methods accurately …
Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad
TJ Gibson, H Dinkel, K Van Roey, F Diella - Cell Communication and …, 2015 - Springer
It has become clear in outline though not yet in detail how cellular regulatory and signalling
systems are constructed. The essential machines are protein complexes that effect …
systems are constructed. The essential machines are protein complexes that effect …