Molecular basis of the functions of the mammalian neuronal growth cone revealed using new methods

M Igarashi - Proceedings of the Japan Academy, Series B, 2019 - jstage.jst.go.jp
The neuronal growth cone is a highly motile, specialized structure for extending neuronal
processes. This structure is essential for nerve growth, axon pathfinding, and accurate …

Identification of functional marker proteins in the mammalian growth cone

M Nozumi, T Togano… - Proceedings of the …, 2009 - National Acad Sciences
Identification of proteins in the mammalian growth cone has the potential to advance our
understanding of this critical regulator of neuronal growth and formation of neural circuit; …

Proteomic identification of the molecular basis of mammalian CNS growth cones

M Igarashi - Neuroscience Research, 2014 - Elsevier
The growth cone, which is a unique structure with high motility that forms at the tips of
extending axons and dendrites, is crucial to neuronal network formation. Axonal growth of …

Click-modified cyclodextrins as nonviral vectors for neuronal siRNA delivery

AM O'Mahony, BMDC Godinho, J Ogier… - ACS chemical …, 2012 - ACS Publications
RNA interference (RNAi) holds great promise as a strategy to further our understanding of
gene function in the central nervous system (CNS) and as a therapeutic approach for …

Visualization of local phosphatidylcholine synthesis within hippocampal neurons using a compartmentalized culture system and imaging mass spectrometry

E Sugiyama, I Yao, M Setou - Biochemical and biophysical research …, 2018 - Elsevier
Neurons extend neurites with an increased synthesis of phosphatidylcholine (PC) that is not
only a membrane component but also a functional regulator with specific fatty acid …

Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells

J Lu, M Nozumi, K Takeuchi, H Abe, M Igarashi - Neuroscience research, 2011 - Elsevier
The growth cone plays crucial roles in neural wiring, synapse formation, and axonal
regeneration. Continuous rearrangement of cytoskeletal elements and targeting of …

[PDF][PDF] Click-modified cyclodextrins as non-viral vectors for neuronal

AM O'Mahony, BMDC Godinho, J Ogier - 2012 - cora.ucc.ie
RNA interference (RNAi) holds great promise as a strategy to further our understanding of
gene function in the central nervous system (CNS) and as a therapeutic approach for …

[PDF][PDF] Click-modified cyclodextrins as non-viral vectors for neuronal siRNA

AM O'Mahony, BMDC Godinho, JR Ogier, M Devocelle… - 2012 - core.ac.uk
RNA interference (RNAi) holds great promise as a strategy to further our understanding of
gene function in the central nervous system (CNS) and as a therapeutic approach for …

[引用][C] 携带人胰岛素基因慢病毒载体转染人脐带间充质干细胞的实验研究

刘毅, 薛美思 - 中国修复重建外科杂志, 2010

[PDF][PDF] 成長円錐のタンパク質構成から観たその機能的分子基盤―プロテオミクスからのアプローチ

五十嵐道弘 - 生化学, 2012 - jbsoc.or.jp
成長円錐は, 発達期の神経細胞の突起先端に形成される運動性に富んだ構造体であり,
脳の複雑な神経回路を形成し, 再編し, 再生する際に決定的に重要な役割を果たす. これまでは …