Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
Endosomal escape pathways for delivery of biologicals
Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in …
efficient and specific delivery of targeted therapeutic agents still remains an issue in …
Strategies in the design of endosomolytic agents for facilitating endosomal escape in nanoparticles
Nanoparticles (NPs) are one of the leading and promising technologies for gene and drug
delivery. However, despite continuous advancements in the delivery of NPs, endosomal …
delivery. However, despite continuous advancements in the delivery of NPs, endosomal …
Nanotherapy for posterior eye diseases
IP Kaur, S Kakkar - Journal of Controlled Release, 2014 - Elsevier
It is assumed that more than 50% of the most enfeebling ocular diseases have their origin in
the posterior segment. Furthermore, most of these diseases lead to partial or complete …
the posterior segment. Furthermore, most of these diseases lead to partial or complete …
Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier
The aims of this work were (i) to evaluate the potential of nanostructured lipid carriers
(NLCs) as a tool to enhance the oral bioavailability of poorly soluble compounds using …
(NLCs) as a tool to enhance the oral bioavailability of poorly soluble compounds using …
A novel cationic niosome formulation for gene delivery to the retina
G Puras, M Mashal, J Zárate, M Agirre, E Ojeda… - Journal of Controlled …, 2014 - Elsevier
Niosomes represent a recent promising approach for gene delivery purposes. We
elaborated on a novel niosome formulation based on the 2, 3-di (tetradecyloxy) propan-1 …
elaborated on a novel niosome formulation based on the 2, 3-di (tetradecyloxy) propan-1 …
Applications of lipid nanoparticles in gene therapy
A del Pozo-Rodriguez, MÁ Solinís… - European Journal of …, 2016 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been
recognized, among the large number of non-viral vectors for gene transfection, as an …
recognized, among the large number of non-viral vectors for gene transfection, as an …
Nanostructured lipid carriers (NLC): the second generation of solid lipid nanoparticles
RH Müller, U Alexiev, P Sinambela… - … chemical methods in …, 2016 - Springer
Solid lipid nanoparticles (SLN) were invented in 1991 as a delivery system combining
advantages of other nanoparticulate systems and at the same time avoiding/minimizing …
advantages of other nanoparticulate systems and at the same time avoiding/minimizing …
Nanoparticle-based drug delivery: case studies for cancer and cardiovascular applications
Nanoparticles (NPs) comprised of nanoengineered complexes are providing new
opportunities for enabling targeted delivery of a range of therapeutics and combinations. A …
opportunities for enabling targeted delivery of a range of therapeutics and combinations. A …
Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles
PS Apaolaza, A del Pozo-Rodríguez, MA Solinís… - Biomaterials, 2016 - Elsevier
X-linked juvenile retinoschisis (XLRS) is a retinal degenerative disorder caused by
mutations in the RS1 gene encoding a protein termed retinoschisin. The disease is an …
mutations in the RS1 gene encoding a protein termed retinoschisin. The disease is an …