Visualization of double stranded DNA in gels with the binding of the fluorescent dye
ethidium bromide has been a basic experimental technique in any molecular biology …

Many biological process and function centers around recognition of double stranded RNA
as it impacts numerous pathways associated with maturation of cellular RNA. This work …

The large-scale conformation of DNA molecules plays a critical role in many basic elements
of cellular functionality and viability. By targeting the structural properties of DNA, many …

The review discusses the theory of interceptor-protector action (the IPA theory) as the new
self-consistent biophysical theory establishing a quantitative interrelation between …

The review discusses the methods of thermodynamic analysis of reactions of non-covalent
binding of biologically active compounds with DNA, which is a key constituent of cell …

In the present study, the interaction of 5-Fluorouracil with herring sperm DNA is reported
using spectroscopic and molecular modeling techniques. This binding study of 5-FU with hs …

The equilibrium binding of ligands (proteins, biologically active compounds, and
oligonucleotides) to nucleic acids underlies many processes in the living cell. Model study …

The investigation of complexes of ethidium bromide (EtBr) and methylene blue (MB) with
DNA at 0.02 M Na+ ionic strength of solution has been carried out. Absorption and …

Atomic force microscopy (AFM) enables determination of physical properties from single
DNA molecules. Insertion of aromatic molecules into the structure of DNA results in …

DNA is the target for many anticancer and antitumor drugs. Therefore determination of the
thermodynamic parameters of ligands-DNA interaction for prediction of biological activity at …