Precision medicine and phenotypes, endotypes, genotypes, regiotypes, and theratypes of allergic diseases

I Agache, CA Akdis - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
A rapidly developing paradigm for modern health care is a proactive and individualized
response to patients' symptoms, combining precision diagnosis and personalized treatment …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Diagnosis and management of NSAID‐Exacerbated Respiratory Disease (N‐ERD)—a EAACI position paper

ML Kowalski, I Agache, S Bavbek, A Bakirtas… - Allergy, 2019 - Wiley Online Library
NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory
disorder of the respiratory tract occurring in patients with asthma and/or chronic …

Recent developments and highlights in biomarkers in allergic diseases and asthma

I Eguiluz‐Gracia, TR Tay, M Hew, MM Escribese… - Allergy, 2018 - Wiley Online Library
The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

NSAID-induced reactions: classification, prevalence, impact, and management strategies

N Blanca-Lopez, V Soriano… - Journal of Asthma …, 2019 - Taylor & Francis
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the leading cause of hypersensitivity
drug reactions. The different chemical structures, cyclooxygenase 1 (COX-1) and/or COX-2 …

Acute severe asthma in adolescent and adult patients: current perspectives on assessment and management

E Kostakou, E Kaniaris, E Filiou, I Vasileiadis… - Journal of clinical …, 2019 - mdpi.com
Asthma is a chronic airway inflammatory disease that is associated with variable expiratory
flow, variable respiratory symptoms, and exacerbations which sometimes require …

Long‐term clinical outcomes of aspirin‐exacerbated respiratory disease: real‐world data from an adult asthma cohort

Y Lee, C Kim, E Lee, HY Lee, SD Woo… - Clinical & …, 2023 - Wiley Online Library
Background Aspirin‐exacerbated respiratory disease (AERD) is a phenotype of severe
asthma, but its disease course has not been well documented compared with that of aspirin …

Recent developments and highlights in rhinitis and allergen immunotherapy

S Reitsma, S Subramaniam, WWJ Fokkens, DY Wang - Allergy, 2018 - Wiley Online Library
This review paper aims to provide an overview of recent developments in the field of allergic
and non‐allergic rhinitis, as well as allergen immunotherapy. Recent advances in …

Burden of chronic oral corticosteroid use by adults with persistent asthma

RS Zeiger, M Schatz, Q Li, W Chen, DB Khatry… - The Journal of Allergy …, 2017 - Elsevier
Background Chronic oral corticosteroid (C-OCS) use in asthma is an indicator of disease
severity, but its risk factors are largely unknown. Objective To describe patient characteristics …

NSAID-exacerbated respiratory disease (NERD): from pathogenesis to improved care

SD Woo, QQ Luu, HS Park - Frontiers in Pharmacology, 2020 - frontiersin.org
Nonsteroidal antiinflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is
characterized by moderate-to-severe asthma and a higher prevalence of chronic …