The prevalence of the metabolic syndrome, a cluster of cardiovascular risk factors
associated with obesity and insulin resistance, is dramatically increasing in Western and …

Although the biochemical steps linking insulin resistance with the metabolic syndrome have
not been completely clarified, mounting experimental and clinical evidence indicate …

There are few data evaluating plasma and/or peripheral blood monocyte cytokine
concentrations/production or attempts to manipulate proinflammatory cytokines in …

Drug-induced liver injury is a significant and still unresolved clinical problem. Limitations to
knowledge about the mechanisms of toxicity render incomplete the detection of hepatotoxic …

Although evidence suggests the link between chronic inflammation and oxidative stress as
the main mechanism responsible for endothelial dysfunction and cardiovascular …

Mitochondrial dysfunction and oxidative stress play a central role in the pathophysiology of
nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the mechanism (s) …

Background Oxidative stress can be defined as an increase in oxidants and/or a decrease in
antioxidant capacity. There is limited information about the oxidative status in subjects with …

In monogamous species, the value of present reproduction is affected by the current
condition of the mate, and females may use male ornaments to evaluate his condition and …

Background Non‐alcoholic fatty liver disease (NAFLD) is the most common cause of
paediatric liver disease. Similar to NAFLD in adults, NAFLD in children is associated with …

Within the so-called ''globesity''epidemic, the Inter-national Obesity Task Force estimated
that there at least 155 million persons are overweight/obese, including 30 to 45 million …