Gut bacterial metabolites such as short-chain fatty acids (SCFAs) have important effects on
immune cells and the gut. SCFAs derive from the fermentation of dietary fiber by gut …

Vaccines are one of the greatest successes of public health, preventing millions of cases of
disease and death in children each year. However, the efficacy of many vaccines can vary …

Diet-derived nutrients are inextricably linked to human physiology by providing energy and
biosynthetic building blocks and by functioning as regulatory molecules. However, the …

Multiple sclerosis (MS), as an autoimmune neurological disease with both genetic and
environmental contribution, still lacks effective treatment options among progressive …

Sepsis is a common critical illness in ICU and always a great difficulty in clinical treatment.
GPR43 (G protein-coupled receptor 43) participates in regulating appetite and …

Fatty acids (FAs) not only are a key component of cellular membrane structure, but also have
diverse functions in biological processes. Recent years have seen great advances in …

Short-chain fatty acids (SCFAs) play an important role in the host system. Among SCFAs,
butyrate has received particular attention for its large effect on host immunity, particularly in …

Microbiota-derived metabolites are important molecules connecting the gut to the brain.
Over the last decade, several studies have highlighted the importance of gut-derived …

Early in the 1900s, it was proposed that health could be improved and senility delayed by
manipulating gut microbiota with the host-friendly bacteria found in yogurt. Later, in 1990 …

CD6 is a lymphocyte-specific scavenger receptor expressed on adaptive (T) and innate
(B1a, NK) immune cells, which is involved in both fine-tuning of lymphocyte activation …