[HTML][HTML] New flavonoids with multiple bronchodilator activity pathways from Tephrosia purpurea L.(Pers.) growing in Saudi Arabia

MS Abdel-Kader, AS Saeedan, NU Rehman… - Saudi Pharmaceutical …, 2024 - Elsevier
Total extract of Tephrosia purpurea (T. purpurea) expressed potent ex-vivo bronchodilator
effect in isolated Guinea pigs' tracheal muscles. Fractionation of Tephrosia purpurea total …

[HTML][HTML] The Detailed Pharmacodynamics of the Gut Relaxant Effect and GC-MS Analysis of the Grewia tenax Fruit Extract: In Vivo and Ex Vivo Approach

NU Rehman, MN Ansari, W Ahmad, M Amir - Molecules, 2022 - mdpi.com
The study was performed to assess and rationalize the traditional utilization of the fruit part of
Grewia tenax (G. tenax). The phytoconstituents present in the methanolic extract were …

[HTML][HTML] Possible Tracheal Relaxant and Antimicrobial Effects of the Essential Oil of Ethiopian Thyme Species (Thymus serrulatus Hochst. ex Benth.): A Multiple …

NU Rehman, MN Ansari, T Haile, A Karim… - Frontiers in …, 2021 - frontiersin.org
The genus Thymus is traditionally used for the treatment of hyperactive airways complaints.
The purpose of the current study is to investigate the potential tracheal relaxant effect and …

[HTML][HTML] TRPV4 Activation during Guinea Pig Airway Smooth Muscle Contraction Promotes Ca2+ and Na+ Influx

LM Montaño, A Carbajal-García… - Pharmaceuticals, 2024 - mdpi.com
Airway smooth muscle (ASM) contraction is determined by the increase in intracellular Ca2+
concentration ([Ca2+] i) caused by its release from the sarcoplasmic reticulum (SR) or by …

[HTML][HTML] Bronchodilator Secondary Metabolites from Rhazya stricta Decne Aerial Parts

MS Abdel-Kader, NU Rehman, AF Aldosari, FS Almutib… - Separations, 2022 - mdpi.com
The plant kingdom comprises medicinally useful plants that have provided many new drugs
used to treat various diseases. In our search for bronchodilator secondary metabolites from …