PdI2-Based Catalysis for Carbonylation Reactions: A Personal Account

R Mancuso, N Della Ca', L Veltri, I Ziccarelli, B Gabriele - Catalysts, 2019 - mdpi.com
In this account, we review our efforts in the field of carbonylation reactions promoted by
palladium iodide-based catalysts, which have proven to be particularly efficient in diverse …

An update on benzofuran inhibitors: a patent review

KM Dawood - Expert Opinion on Therapeutic Patents, 2019 - Taylor & Francis
Introduction: Benzofuran is a fundamental unit in numerous bioactive heterocycles. They
have attracted chemists and medical researchers due to their broad range of biological …

A smart nanovector for cancer targeted drug delivery based on graphene quantum dots

D Iannazzo, A Pistone, C Celesti, C Triolo, S Patané… - Nanomaterials, 2019 - mdpi.com
Graphene quantum dots (GQD), the new generation members of graphene-family, have
shown promising applications in anticancer therapy. In this study, we report the synthesis of …

Leptin modulates exosome biogenesis in breast cancer cells: an additional mechanism in cell-to-cell communication

C Giordano, L Gelsomino, I Barone, S Panza… - Journal of Clinical …, 2019 - mdpi.com
Exosomes—small membrane vesicles secreted by both normal and malignant cells upon
fusion of endosomal multivesicular bodies (MVBs) with the plasma membrane—play an …

Synthesis and molecular docking study of new benzofuran and furo [3, 2-g] chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors

KM Amin, YM Syam, MM Anwar, HI Ali… - Bioorganic …, 2018 - Elsevier
This study deals with synthesis of a new set of benzofuran and 5 H-furo [3, 2-g] chromone
linked various heterocyclic functionalities using concise synthetic approaches aiming to gain …

A comparative study of the anticancer activity and PARP-1 inhibiting effect of benzofuran–pyrazole scaffold and its nano-sized particles in human breast cancer cells

MM Anwar, SS Abd El-Karim, AH Mahmoud, AEGE Amr… - Molecules, 2019 - mdpi.com
Breast cancer is considered the most common and deadly cancer among women worldwide.
Nanomedicine has become extremely attractive in the field of cancer treatment. Due to the …

Knockdown of the prognostic cancer stem cell marker Musashi-1 decreases radio-resistance while enhancing apoptosis in hormone receptor-positive breast cancer …

FM Troschel, H Palenta, K Borrmann, K Heshe… - Journal of Cancer …, 2021 - Springer
Purpose While the stem cell marker Musashi-1 (MSI-1) has been identified as a key player in
a wide array of malignancies, few findings exist on its prognostic relevance and relevance …

Evidence for enhanced exosome production in aromatase inhibitor-resistant breast cancer cells

G Augimeri, G La Camera, L Gelsomino… - International Journal of …, 2020 - mdpi.com
Aromatase inhibitors (AIs) represent the standard anti-hormonal therapy for post-
menopausal estrogen receptor-positive breast cancer, but their efficacy is limited by the …

Hypervalent iodine (III)-catalyzed synthesis of 2-arylbenzofurans

FV Singh, SR Mangaonkar - Synthesis, 2018 - thieme-connect.com
An alternative route for the synthesis of 2-arylbenzofurans is described by iodine (III)-
catalyzed oxidative cyclization of 2-hydroxystilbenes using 10 mol%(diacetoxyiodo) …

Multicomponent Synthesis of Benzothiophen‐2‐acetic Esters by a Palladium Iodide Catalyzed S‐cyclization – Alkoxycarbonylation Sequence

R Mancuso, M Lettieri, I Ziccarelli… - Advanced Synthesis …, 2021 - Wiley Online Library
A catalytic carbonylative approach to the multicomponent synthesis of benzothiophene
derivatives from simple building blocks [1‐(2‐(methylthio) phenyl) prop‐2‐yn‐1‐ols, carbon …