Increased work of breathing due to tracheomalacia in neonates

CC Gunatilaka, NS Higano, EB Hysinger… - Annals of the …, 2020 - atsjournals.org
Rationale: Dynamic collapse of the tracheal lumen (tracheomalacia) occurs frequently in
premature neonates, particularly in those with common comorbidities such as …

Ultrashort echo-time MRI for the assessment of tracheomalacia in neonates

EB Hysinger, AJ Bates, NS Higano, D Benscoter… - Chest, 2020 - Elsevier
Background Bronchoscopy is the gold standard for evaluating tracheomalacia; however,
reliance on an invasive procedure limits understanding of normal airway dynamics. Self …

Assessing the relationship between movement and airflow in the upper airway using computational fluid dynamics with motion determined from magnetic resonance …

AJ Bates, A Schuh, G Amine-Eddine, K McConnell… - Clinical …, 2019 - Elsevier
Background Computational fluid dynamics simulations of respiratory airflow in the upper
airway reveal clinically relevant information, including sites of local resistance, inhaled …

[HTML][HTML] The effects of curvature and constriction on airflow and energy loss in pathological tracheas

AJ Bates, R Cetto, DJ Doorly, RC Schroter… - Respiratory physiology …, 2016 - Elsevier
This paper considers factors that play a significant role in determining inspiratory pressure
and energy losses in the human trachea. Previous characterisations of pathological …

Quantitative Assessment of Regional Dynamic Airway Collapse in Neonates via Retrospectively Respiratory‐Gated 1H Ultrashort Echo Time MRI

AJ Bates, NS Higano, EB Hysinger… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Neonatal dynamic tracheal collapse (tracheomalacia, TM) is a common and
serious comorbidity in infants, particularly those with chronic lung disease of prematurity …

Effects of glottis motion on airflow and energy expenditure in a human upper airway model

J Xi, XA Si, H Dong, H Zhong - European Journal of Mechanics-B/Fluids, 2018 - Elsevier
The periodic movement of the glottal aperture during tidal breathing has been long
recognized as a physiological factor in regulating the respiratory airflow dynamics. However …

Flow features and micro-particle deposition in a human respiratory system during sniffing

H Calmet, G Houzeaux, M Vázquez, B Eguzkitza… - Journal of Aerosol …, 2018 - Elsevier
As we inhale, the air drawn through our nose undergoes successive accelerations and
decelerations as it is turned, split and recombined before splitting again at the end of the …

The effect of airway motion and breathing phase during imaging on CFD simulations of respiratory airflow

CC Gunatilaka, A Schuh, NS Higano, JC Woods… - Computers in biology …, 2020 - Elsevier
Rationale Computational fluid dynamics (CFD) simulations of respiratory airflow can quantify
clinically useful information that cannot be obtained directly, such as the work of breathing …

A novel method to generate dynamic boundary conditions for airway CFD by mapping upper airway movement with non‐rigid registration of dynamic and static MRI

AJ Bates, A Schuh, K McConnell… - International Journal …, 2018 - Wiley Online Library
Computational fluid dynamics (CFD) simulations of airflow in the human airways have the
potential to provide a great deal of information that can aid clinicians in case management …

Computational modelling of the respiratory system: discussion of coupled modelling approaches and two recent extensions

CJ Roth, L Yoshihara, M Ismail, WA Wall - Computer Methods in Applied …, 2017 - Elsevier
In this article we present advanced computational models of the respiratory system with a
special focus on approaches that are able to tackle the interaction between flow and tissue …