Maternal obesity in pregnancy impacts offspring cardiometabolic health: Systematic review and meta‐analysis of animal studies

MD Menting, S Mintjens, C van de Beek… - Obesity …, 2019 - Wiley Online Library
Obesity before and during pregnancy leads to reduced offspring cardiometabolic health.
Here, we systematically reviewed animal experimental evidence of maternal obesity before …

Small cells with big implications: microglia and sex differences in brain development, plasticity and behavioral health

LH Nelson, AI Saulsbery, KM Lenz - Progress in neurobiology, 2019 - Elsevier
Brain sex differences are programmed largely by sex hormone secretions and direct sex
chromosome effects in early life, and are subsequently modulated by early life experiences …

Effects of high-fat diets on fetal growth in rodents: a systematic review

JK Christians, KI Lennie, LK Wild, R Garcha - Reproductive Biology and …, 2019 - Springer
Background Maternal nutrition during pregnancy has life-long consequences for offspring.
However, the effects of maternal overnutrition and/or obesity on fetal growth remain poorly …

[HTML][HTML] The link between maternal obesity and offspring neurobehavior: a systematic review of animal experiments

MD Menting, C van de Beek, S Mintjens… - … & biobehavioral reviews, 2019 - Elsevier
Maternal obesity in pregnancy is associated with neurobehavioral problems in the offspring.
Establishing causality has been challenging in existing human studies, due to confounding …

The placenta's role in sexually dimorphic fetal growth strategies

JK Christians - Reproductive Sciences, 2022 - Springer
Fetal sex affects the risk of pregnancy complications and the long-term effects of prenatal
environment on health. Some have hypothesized that growth strategies differ between the …

Transgenerational effects of obesogenic diets in rodents: A meta‐analysis

H Anwer, MJ Morris, DWA Noble, S Nakagawa… - Obesity …, 2022 - Wiley Online Library
Obesity is a major health condition that affects millions worldwide. There is an increased
interest in understanding the adverse outcomes associated with obesogenic diets. A …

Maternal sweeteners intake modulates gut microbiota and exacerbates learning and memory processes in adult male offspring

AL de la Garza, B Romero-Delgado… - Frontiers in …, 2022 - frontiersin.org
Background: There is increasing evidence that gut microbiota in offspring is derived in part
from maternal environment such as diet. Thus, sweeteners intake including caloric or non …

Maternal high‐sugar diet results in NMDA receptors abnormalities and cognitive impairment in rat offspring

J Mizera, G Kazek, E Niedzielska‐Andres… - The FASEB …, 2021 - Wiley Online Library
Cognitive impairment affects patients suffering from various neuropsychiatric diseases,
which are often accompanied by changes in the glutamatergic system. Epidemiological …

Maternal high-fat or low-protein diets promote autism-related behavior and altered social behavior within groups in offspring male mice

N Zilkha, SG Chuartzman, R Fishman, S Ben-Dor… - Scientific Reports, 2024 - nature.com
Maternal malnutrition has been associated with neurodevelopmental deficits and long-term
implications on the offspring's health and behavior. Here, we investigated the effects of …

Obesogenic diet exposure alters uterine natural killer cell biology and impairs vasculature remodeling in mice

J Baltayeva, C Konwar, B Castellana… - Biology of …, 2020 - academic.oup.com
Prepregnancy obesity associates with adverse reproductive outcomes that impact maternal
and fetal health. While obesity-driven mechanisms underlying adverse pregnancy outcomes …