Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture

JRS Meadows, JM Kidd, GD Wang, HG Parker… - Genome biology, 2023 - Springer
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

Plant-ImputeDB: an integrated multiple plant reference panel database for genotype imputation

Y Gao, Z Yang, W Yang, Y Yang, J Gong… - Nucleic Acids …, 2021 - academic.oup.com
Genotype imputation is a process that estimates missing genotypes in terms of the
haplotypes and genotypes in a reference panel. It can effectively increase the density of …

SNP‐based heritability and genetic architecture of cranial cruciate ligament rupture in Labrador Retrievers

SR Cook, MG Conzemius, ME McCue… - Animal …, 2020 - Wiley Online Library
Cranial cruciate ligament rupture (CCLR) is one of the leading causes of pelvic limb
lameness in dogs. About 6% of Labrador Retrievers suffer from this orthopedic problem. The …

Improving the resolution of canine genome‐wide association studies using genotype imputation: A study of two breeds

CA Jenkins… - Animal …, 2021 - Wiley Online Library
Genotype imputation using a reference panel that combines high‐density array data and
publicly available whole genome sequence consortium variant data is potentially a cost …

A Pipeline for Phasing and Genotype Imputation on Mixed Human Data (Parents-Offspring Trios and Unrelated Subjects) by Reviewing Current Methods and Software

GN Baldrighi, A Nova, L Bernardinelli, T Fazia - Life, 2022 - mdpi.com
Genotype imputation has become an essential prerequisite when performing association
analysis. It is a computational technique that allows us to infer genetic markers that have not …

Assessing accuracy of genotype imputation in the afrikaner and brahman cattle breeds of South Africa

S Mdyogolo, MD MacNeil, FWC Neser… - Tropical Animal Health …, 2022 - Springer
Imputation may be used to rescue genomic data from animals that would otherwise be
eliminated due to a lower than desired call rate. The aim of this study was to compare the …

Genetic Investigations of Canine Idiopathic Epilepsy and Movement Disorders

CA Jenkins - 2023 - search.proquest.com
Dogs represent a fascinating species with dramatic variation in traits across hundreds of
breeds. Genetic bottlenecks, inbreeding, and selection for extreme phenotypes have led to …

The importance of disease incidence rate on performance of GBLUP, threshold BayesA and machine learning methods in original and imputed data set

Y Naderi, S Sadeghi - Spanish Journal of Agricultural Research, 2020 - sjar.revistas.csic.es
Aim of study: To predict genomic accuracy of binary traits considering different rates of
disease incidence. Area of study: Simulation Material and methods: Two machine learning …

Siccuracy: An R-package for executing genotype imputation strategy simulations with AlphaImpute

SMK Edwards - bioRxiv, 2017 - biorxiv.org
Background The reported R-package provides an easy way for executing and evaluating
genotype imputation studies, by providing functions for preparing input files for AlphaImpute …