[HTML][HTML] Turning cold tumors into hot tumors by improving T-cell infiltration
YT Liu, ZJ Sun - Theranostics, 2021 - ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
Bioengineered nanogels for cancer immunotherapy
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
Type I interferon-mediated tumor immunity and its role in immunotherapy
R Yu, B Zhu, D Chen - Cellular and Molecular Life Sciences, 2022 - Springer
Immune checkpoint blockade (ICB) therapies have achieved remarkable clinical responses
in patients with many different types of cancer; however, most patients who receive ICB …
in patients with many different types of cancer; however, most patients who receive ICB …
[HTML][HTML] Antibody–drug conjugates: in search of partners of choice
J Fuentes-Antrás, S Genta, A Vijenthira, LL Siu - Trends in cancer, 2023 - cell.com
Antibody–drug conjugates (ADCs) have become a credentialled class of anticancer drugs
for both solid and hematological malignancies, with regulatory approvals mainly as single …
for both solid and hematological malignancies, with regulatory approvals mainly as single …
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …
survival have been modest and, in some examples, less than those of other approved …
Nanogels: Synthesis, properties, and recent biomedical applications
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
Biomineralized bacterial outer membrane vesicles potentiate safe and efficient tumor microenvironment reprogramming for anticancer therapy
S Qing, C Lyu, L Zhu, C Pan, S Wang, F Li… - Advanced …, 2020 - Wiley Online Library
The highly immunosuppressive tumor microenvironment (TME) in solid tumors often
dampens the efficacy of immunotherapy. In this study, bacterial outer membrane vesicles …
dampens the efficacy of immunotherapy. In this study, bacterial outer membrane vesicles …
Tailoring nanomaterials for targeting tumor‐associated macrophages
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …
immunology have paved the way for the development of more personalized cancer immuno …
[HTML][HTML] Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants
Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …
[HTML][HTML] Symphony of nanomaterials and immunotherapy based on the cancer–immunity cycle
The immune system is involved in the initiation and progression of cancer. Research on
cancer and immunity has contributed to the development of several clinically successful …
cancer and immunity has contributed to the development of several clinically successful …