[HTML][HTML] Turning cold tumors into hot tumors by improving T-cell infiltration

YT Liu, ZJ Sun - Theranostics, 2021 - ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …

Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Type I interferon-mediated tumor immunity and its role in immunotherapy

R Yu, B Zhu, D Chen - Cellular and Molecular Life Sciences, 2022 - Springer
Immune checkpoint blockade (ICB) therapies have achieved remarkable clinical responses
in patients with many different types of cancer; however, most patients who receive ICB …

[HTML][HTML] Antibody–drug conjugates: in search of partners of choice

J Fuentes-Antrás, S Genta, A Vijenthira, LL Siu - Trends in cancer, 2023 - cell.com
Antibody–drug conjugates (ADCs) have become a credentialled class of anticancer drugs
for both solid and hematological malignancies, with regulatory approvals mainly as single …

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

JD Martin, H Cabral, T Stylianopoulos… - Nature reviews Clinical …, 2020 - nature.com
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Biomineralized bacterial outer membrane vesicles potentiate safe and efficient tumor microenvironment reprogramming for anticancer therapy

S Qing, C Lyu, L Zhu, C Pan, S Wang, F Li… - Advanced …, 2020 - Wiley Online Library
The highly immunosuppressive tumor microenvironment (TME) in solid tumors often
dampens the efficacy of immunotherapy. In this study, bacterial outer membrane vesicles …

Tailoring nanomaterials for targeting tumor‐associated macrophages

M Ovais, M Guo, C Chen - Advanced materials, 2019 - Wiley Online Library
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …

[HTML][HTML] Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

S Bhagchandani, JA Johnson, DJ Irvine - Advanced drug delivery reviews, 2021 - Elsevier
Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …

[HTML][HTML] Symphony of nanomaterials and immunotherapy based on the cancer–immunity cycle

Q Li, Z Shi, F Zhang, W Zeng, D Zhu, L Mei - Acta Pharmaceutica Sinica B, 2022 - Elsevier
The immune system is involved in the initiation and progression of cancer. Research on
cancer and immunity has contributed to the development of several clinically successful …