Improving helminth genome resources in the post-genomic era

SR Doyle - Trends in parasitology, 2022 - cell.com
Rapid advancement in high-throughput sequencing and analytical approaches has seen a
steady increase in the generation of genomic resources for helminth parasites. Now …

Tanacetum species: Bridging empirical knowledge, phytochemistry, nutritional value, health benefits and clinical evidence

S Khatib, M Sobeh, C Faraloni… - Frontiers in …, 2023 - frontiersin.org
Introduction: The Tanacetum genus consists of 160 accepted flowering species thriving
throughout temperate regions, mainly in the Mediterranean Basin, Northern America, and …

Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel β …

A Venkatesan, PD Jimenez Castro, A Morosetti… - PLoS …, 2023 - journals.plos.org
Ancylostoma caninum is an important zoonotic gastrointestinal nematode of dogs worldwide
and a close relative of human hookworms. We recently reported that racing greyhound dogs …

Ancient diversity in host-parasite interaction genes in a model parasitic nematode

L Stevens, I Martínez-Ugalde, E King, M Wagah… - Nature …, 2023 - nature.com
Host-parasite interactions exert strong selection pressures on the genomes of both host and
parasite. These interactions can lead to negative frequency-dependent selection, a form of …

New paradigms in research on Dirofilaria immitis

TG Geary - Parasites & Vectors, 2023 - Springer
Background Since the advent of ivermectin (along with melarsomine and doxycycline),
heartworm has come to be viewed as a solved problem in veterinary medicine, diminishing …

Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode

R Laing, SR Doyle, J McIntyre, K Maitland… - PLoS …, 2022 - journals.plos.org
The antiparasitic drug ivermectin plays an essential role in human and animal health
globally. However, ivermectin resistance is widespread in veterinary helminths and there are …

[HTML][HTML] Ascaridia galli-An old problem that requires new solutions

J Höglund, G Daş, B Tarbiat, P Geldhof… - International Journal for …, 2023 - Elsevier
Reports of Ascaridia galli in laying hens in Europe have increased since the ban on
conventional battery cages in 2012. As this parasite is transmitted directly via the faecal-oral …

Ivermectin and albendazole coadministration: opportunities for strongyloidiasis control

J Gandasegui, C Onwuchekwa… - The Lancet Infectious …, 2022 - thelancet.com
In 2020, WHO recognised the importance of strongyloidiasis alongside soil-transmitted
helminths (STH) in their 2021–30 roadmap, which aspires to target Strongyloides stercoralis …

[HTML][HTML] A mixed amplicon metabarcoding and sequencing approach for surveillance of drug resistance to levamisole and benzimidazole in Haemonchus spp.

EK Francis, A Antonopoulos, ME Westman… - International Journal for …, 2024 - Elsevier
Anthelmintic-resistant parasitic nematodes present a significant threat to sustainable
livestock production worldwide. The ability to detect the emergence of anthelmintic …

[HTML][HTML] Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus

A Antonopoulos, SR Doyle, DJ Bartley… - International Journal for …, 2022 - Elsevier
Haemonchus contortus is a haematophagous parasitic nematode that infects small
ruminants and causes significant animal health concerns and economic losses within the …