Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic
imaging. In a narrow sense, molecular imaging means genetic imaging and can be called …

Anatomical cross‐sectional imaging methods such as contrast‐enhanced MRI and CT are
the standard for the delineation, treatment planning, and follow‐up of patients with …

Implantation of reporter-labeled tumor cells in an immunocompetent host involves a risk of
their immune elimination. We have studied this effect in a mouse model of breast cancer …

Autotaxin is a secreted enzyme that produces most extracellular lysophosphatidate, which
stimulates 6 G‐protein‐coupled receptors. Lysophosphatidate promotes cancer cell survival …

Near‐infrared photoimmunotherapy (NIR‐PIT) is a cancer treatment that utilizes antibody‐
photoabsorber (IR700) conjugates to selectively kill target cells by exposing them to NIR …

In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for
vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and …

Simple Summary This experimental study was designed in order to investigate the efficacy
of the triple combination of radiation (SBRT), PD-1 blockade, and OX40 co-stimulation in a …

Human cancers modeled in Genetically Engineered Mouse Models (GEMM s) can provide
important mechanistic insights into the molecular basis of tumor development and enable …

Introduction We hypothesised that the combined use of radiation therapy and a
phosphoinositide 3-kinaseγδ inhibitor to reduce immune suppression would enhance the …

Preclinical models that reliably recapitulate the immunosuppressive properties of human
gliomas are essential to assess immune-based therapies. GL261 murine glioma cells are …