Proliferation and differentiation inside erythrocytes are important steps in the life cycle of
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …

The malaria parasite is the most important member of the Apicomplexa, a large and highly
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …

Identifying the genomic changes that underlie phenotypic adaptations is a key challenge in
evolutionary biology and genomics. Loss of protein-coding genes is one type of genomic …

Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …

The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …

Exported proteins of the malaria parasite Plasmodium falciparum interact with proteins of the
erythrocyte membrane and induce substantial changes in the morphology, physiology and …

The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …

An immunovariant adhesion protein family in Plasmodium falciparum named erythrocyte
membrane protein 1 (PfEMP1), encoded by var genes, is responsible for both antigenic …

Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …

Invasion of erythrocytes is a prerequisite in the life history of the malaria parasite. Members
of the reticulocyte-binding homologue family (PfRh) have been implicated in the invasion …