Engineering an artificial catch bond using mechanical anisotropy
Catch bonds are a rare class of protein-protein interactions where the bond lifetime
increases under an external pulling force. Here, we report how modification of anchor …
increases under an external pulling force. Here, we report how modification of anchor …
S373P mutation stabilizes the receptor-binding domain of the spike protein in omicron and promotes binding
A cluster of several newly occurring mutations on Omicron is found at the β-core region of
the spike protein's receptor-binding domain (RBD), where mutation rarely happened before …
the spike protein's receptor-binding domain (RBD), where mutation rarely happened before …
Iterative Machine Learning for Classification and Discovery of Single-Molecule Unfolding Trajectories from Force Spectroscopy Data
We report the application of machine learning techniques to expedite classification and
analysis of protein unfolding trajectories from force spectroscopy data. Using kernel …
analysis of protein unfolding trajectories from force spectroscopy data. Using kernel …
[HTML][HTML] Mechanistic basis of staphylococcal interspecies competition for skin colonization
JJ Maciag, C Chantraine, KB Mills, R Yadav… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Staphylococci, whether beneficial commensals or pathogens, often colonize human skin,
potentially leading to competition for the same niche. In this multidisciplinary study we …
potentially leading to competition for the same niche. In this multidisciplinary study we …