Computer‐aided drug design to explore cyclodextrin therapeutics and biomedical applications

A Abdolmaleki, F Ghasemi… - Chemical Biology & Drug …, 2017 - Wiley Online Library
Cyclodextrin (CD) is a subset of the macrocyclic structural class, which is an important class
of small organic agents that are useful functional excipients. They have wide range …

Physicochemical characterization of cyclodextrin–drug interactions in the solid state and the effect of water on these interactions

N Ogawa, C Takahashi, H Yamamoto - Journal of Pharmaceutical Sciences, 2015 - Elsevier
The characterization of cyclodextrin (CD)–drug interactions has encountered difficulties in
the solid state, especially of amorphous state. However, recent advances in experimental …

Chloramphenicol· cyclodextrin inclusion compounds: Co-dissolution and mechanochemical preparations and antibacterial action

AI Ramos, TM Braga, P Silva, JA Fernandes… - …, 2013 - pubs.rsc.org
β-Cyclodextrin (βCD) inclusion compounds of chloramphenicol in the solid-state were
prepared via two different procedures, co-crystallisation from aqueous solution and the …

Constructing hollow carbon sphere liquid with permanent porosity via electrostatic modification of polyionic liquids for CO2 gas adsorption

F Su, X Li, Y Wang, Z He, L Fan, H Wang, J Xie… - Separation and …, 2021 - Elsevier
Porous liquids (PLs) are a type of porous materials that combine the porosity of solids and
fluidity of liquids, which has attracted widespread attention. In this paper, we report a new …

Synthesis, characterization and antitumor activity of 1, 2-disubstituted ferrocenes and cyclodextrin inclusion complexes

Ž Petrovski, MRPN de Matos, SS Braga… - Journal of …, 2008 - Elsevier
Seven different ferrocene derivatives have been tested in vitro against Ehrlich ascites tumor
cells. Neither ferrocene nor the monosubstituted derivative N, N …

Effects of cogrinding with β-cyclodextrin on the solid state fentanyl

N Ogawa, K Higashi, H Nagase, T Endo… - Journal of …, 2010 - Elsevier
Fentanyl base and β-cyclodextrin (β-CD) were coground at 1: 1 and 1: 2 molar ratios
(fentanyl: β-CD) and the physicochemical characteristics of the mixtures were studied using …

Inclusive separation of acetophenone from petrochemical by‐product with 1‐phenylethanol via noncovalent interactions

K Chai, H Ji - AIChE Journal, 2014 - Wiley Online Library
Separation of the barely studied mixture of acetophenone and 1‐phenylethanol, a typical by‐
product obtained by oil refinery plant, based on the preferential affinity of β‐cyclodextrin …

Determination of binding strengths of a host− guest complex using resonance Raman scattering

EH Witlicki, SW Hansen, M Christensen… - The Journal of …, 2009 - ACS Publications
The detection of analyte-binding events by receptors is drawing together the fields of Raman
spectroscopy and supramolecular chemistry. This study is intended to facilitate this cohering …

Inclusion complexes of the antitumour metallocenes Cp2MCl2 (M= Mo, Ti) with cucurbit [n] urils

DP Buck, PM Abeysinghe, C Cullinane, AI Day… - Dalton …, 2008 - pubs.rsc.org
The encapsulation of the aquated forms of molybdocene dichloride and titanocene
dichloride by cucurbit [n] uril (Q [n], where n= 7 and 8) at different pD values has been …

Are cucurbiturils better drug carriers for bent metallocenes? Insights from theory

D Senthilnathan, RV Solomon, S Kiruthika… - JBIC Journal of …, 2018 - Springer
Bent metallocenes (BM) have anti-tumor properties but they face a serious drug efficacy
problem due to poor aqueous solubility and rapid hydrolysis under physiological conditions …