The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

Candida auris is a recently emerged multidrug-resistant fungal pathogen causing severe
illness in hospitalized patients. C. auris is most closely related to a few environmental or …

Tolerance to antifungal drug concentrations above the minimal inhibitory concentration
(MIC) is rarely quantified, and current clinical recommendations suggest it should be …

We evaluated the epidemiology of Candida bloodstream infections in the neonatal intensive
care unit (NICU) of an Italian university hospital during a 9‐year period as a means of …

Candidemia, the commonest invasive fungal infection, is associated with high morbidity and
mortality in developing countries, though the exact prevalence is not known due to lack of …

Fluconazole (FLC) tolerant phenotypes in Candida species contribute to persistent
candidemia and the emergence of FLC resistance. Therefore, making FLC fungicidal and …

In recent decades, the epidemiology of invasive candidiasis (IC) has progressively changed
worldwide. This notably includes emergence of several Candida species. Although some …

Objective Current knowledge on the global burden of infant sepsis is limited to population-
level data. We aimed to summarize global case fatality rates (CFRs) of young infants with …

This study aimed to determine the predictors of persistent candidemia and examine the
impact of biofilm formation by Candida isolates in adult patients with candidemia. Of the …

Objectives Candida albicans is an important fungal pathogen that can cause life-threatening
disseminated infections. To determine the efficacy of therapy in murine models, a …