Echocardiography in pulmonary arterial hypertension: from diagnosis to prognosis

E Bossone, A D'Andrea, M D'Alto, R Citro… - Journal of the American …, 2013 - Elsevier
Pulmonary arterial hypertension is most often diagnosed in its advanced stages because of
the nonspecific nature of early symptoms and signs. Although clinical assessment is …

Walking dead tumor cells for targeted drug delivery against lung metastasis of triple‐negative breast cancer

Z Zhao, L Fang, P Xiao, X Sun, L Zhou, X Liu… - Advanced …, 2022 - Wiley Online Library
Lung metastasis is challenging in patients with triple‐negative breast cancer (TNBC).
Surgery is always not available due to the dissemination of metastatic foci and most drugs …

Pulmonary hypertension and the right ventricle in hypoxia

R Naeije, C Dedobbeleer - Experimental physiology, 2013 - Wiley Online Library
New Findings• What is the topic of this review? Studies a, contabs, longabsre reviewed
showing that hypoxic pulmonary vasoconstriction and subsequent remodelling expose the …

Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension

M D'Alto, E Romeo, P Argiento, A D'Andrea… - International journal of …, 2013 - Elsevier
Background Echocardiographic studies have contributed to progress in the understanding of
the pathophysiology of the pulmonary circulation and have been shown to be useful for …

Aging and anatomical variations in lung tissue stiffness

D Sicard, AJ Haak, KM Choi, AR Craig… - … of Physiology-Lung …, 2018 - journals.physiology.org
Lung function is inherently mechanical in nature and depends on the capacity to conduct air
and blood to and from the gas exchange regions. Variations in the elastic properties of the …

Metabolic profiling of right ventricular-pulmonary vascular function reveals circulating biomarkers of pulmonary hypertension

GD Lewis, D Ngo, AR Hemnes, L Farrell… - Journal of the American …, 2016 - jacc.org
Background: Pulmonary hypertension and associated right ventricular (RV) dysfunction are
important determinants of morbidity and mortality, which are optimally characterized by …

Pulmonary vascular distensibility predicts pulmonary hypertension severity, exercise capacity, and survival in heart failure

R Malhotra, BP Dhakal, AS Eisman… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Pulmonary vascular (PV) distensibility, defined as the percent increase in
pulmonary vessel diameter per mm Hg increase in pressure, permits the pulmonary vessels …

Pulmonary hypertension and chronic mountain sickness

R Naeije, R Vanderpool - High altitude medicine & biology, 2013 - liebertpub.com
Abstract Naeije, Robert, and Rebecca Vanderpool. Pulmonary hypertension and chronic
mountain sickness. High Alt Med Biol 14: 117–125, 2013.—Chronic mountain sickness is a …

Physiology of the pulmonary circulation and the right heart

R Naeije - Current hypertension reports, 2013 - Springer
The pulmonary circulation is a high-flow and low-pressure circuit. The functional state of the
pulmonary circulation is defined by pulmonary vascular pressure–flow relationships …

Simultaneous measurement of lung diffusing capacity and pulmonary hemodynamics reveals exertional alveolar‐capillary dysfunction in heart failure with preserved …

CC Fermoyle, GM Stewart, BA Borlaug… - Journal of the …, 2021 - Am Heart Assoc
Background Hemodynamic perturbations in heart failure with preserved ejection fraction
(HFpEF) may alter the distribution of blood in the lungs, impair gas transfer from the alveoli …