The dynamic lung microbiome in health and disease
JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …
light into the microbial world of the respiratory tract. Long considered to be a sterile …
Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention
E von Mutius, HH Smits - The Lancet, 2020 - thelancet.com
Asthma is a complex disease that often starts in childhood. Genomic and environmental
factors as well as aberrant immune maturation early in life can contribute to the onset of …
factors as well as aberrant immune maturation early in life can contribute to the onset of …
The infant gut virome is associated with preschool asthma risk independently of bacteria
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …
on the structure and functioning of bacterial populations, but their roles and association with …
Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma
H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …
combining precision diagnosis and personalized treatment. Accordingly, the approach to …
Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma
There have been reports of associations between cesarean section delivery and the risk of
childhood asthma, potentially mediated through changes in the gut microbiota. We followed …
childhood asthma, potentially mediated through changes in the gut microbiota. We followed …
Early-life respiratory infections and developmental immunity determine lifelong lung health
Respiratory infections are common in infants and young children. However, the immune
system develops and matures as the child grows, thus the effects of infection during this time …
system develops and matures as the child grows, thus the effects of infection during this time …
Early life microbiota and respiratory tract infections
WAA de Steenhuijsen Piters, J Binkowska, D Bogaert - Cell Host & Microbe, 2020 - cell.com
Over the last decade, it has become clear that respiratory and intestinal tract microbiota are
related to pathogenesis of respiratory tract infections (RTIs). Host and environmental factors …
related to pathogenesis of respiratory tract infections (RTIs). Host and environmental factors …
Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk
Background Studies indicate that the nasal microbiome may correlate strongly with the
presence or future risk of childhood asthma. Objectives In this study, we tested whether …
presence or future risk of childhood asthma. Objectives In this study, we tested whether …
Urbanized microbiota in infants, immune constitution, and later risk of atopic diseases
Background Urbanization is linked with an increased burden of asthma and atopic traits. A
putative mechanism is insufficient exposure to beneficial microbes early in life, leading to …
putative mechanism is insufficient exposure to beneficial microbes early in life, leading to …
Microbiome and asthma: microbial dysbiosis and the origins, phenotypes, persistence, and severity of asthma
J Valverde-Molina, L García-Marcos - Nutrients, 2023 - mdpi.com
The importance of the microbiome, and of the gut-lung axis in the origin and persistence of
asthma, is an ongoing field of investigation. The process of microbial colonisation in the first …
asthma, is an ongoing field of investigation. The process of microbial colonisation in the first …