Hydrogen sulfide and carnosine: modulation of oxidative stress and inflammation in kidney and brain axis

V Calabrese, M Scuto, AT Salinaro, G Dionisio… - Antioxidants, 2020 - mdpi.com
Emerging evidence indicates that the dysregulation of cellular redox homeostasis and
chronic inflammatory processes are implicated in the pathogenesis of kidney and brain …

[HTML][HTML] Self-eating: friend or foe? The emerging role of autophagy in fibrotic diseases

Y Li, R Liu, J Wu, X Li - Theranostics, 2020 - ncbi.nlm.nih.gov
Fibrosis occurs in most human organs including the liver, lung, heart and kidney, and is
crucial for the progression of most chronic diseases. As an indispensable catabolic process …

[HTML][HTML] Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway

R Montanaro, V Vellecco, R Torregrossa, GM Casillo… - Redox Biology, 2023 - Elsevier
Diabetes is associated with severe vascular complications involving the impairment of
endothelial nitric oxide synthase (eNOS) as well as cystathionine γ-lyase (CSE) activity …

Metformin accelerates myelin recovery and ameliorates behavioral deficits in the animal model of multiple sclerosis via adjustment of AMPK/Nrf2/mTOR signaling and …

N Sanadgol, M Barati, F Houshmand, S Hassani… - Pharmacological …, 2020 - Springer
Background Multiple sclerosis (MS) is a devastating autoimmune disorder characterized by
oligodendrocytes (OLGs) loss and demyelination. In this study, we have examined the …

Kidney diseases and COVID-19 infection: causes and effect, supportive therapeutics and nutritional perspectives

H Askari, N Sanadgol, A Azarnezhad, A Tajbakhsh… - Heliyon, 2021 - cell.com
Recently, the novel coronavirus disease 2019 (COVID-19), has attracted the attention of
scientists where it has a high mortality rate among older adults and individuals suffering from …

Hydrogen sulfide and the kidney: physiological roles, contribution to pathophysiology, and therapeutic potential

M Peleli, P Zampas… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Hydrogen sulfide (H2S), the third member of the gasotransmitter family, has a
broad spectrum of biological activities, including antioxidant and cytoprotective actions, as …

Low-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1–7 and vasopressin✰,✰✰

HL Corrêa, RVP Neves, LA Deus, BCH Maia… - Physiology & …, 2021 - Elsevier
Aims We sought to investigate the effect of resistance training (RT) and low-load RT with
moderate blood flow restriction (RT+ BFR) on blood pressure, exercise pressor response …

Roles of hydrogen sulfide donors in common kidney diseases

EE Ngowi, M Sarfraz, A Afzal, NH Khan… - Frontiers in …, 2020 - frontiersin.org
Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in
mammals. The decline in H2S level has been reported in numerous renal disorders. In …

Relationship between lysosomal dyshomeostasis and progression of diabetic kidney disease

M Wu, M Zhang, Y Zhang, Z Li, X Li, Z Liu, H Liu… - Cell Death & …, 2021 - nature.com
Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular
material circulation. They play a key role in the maintenance of cellular physiological …

An updated review of various medicinal applications of p-Co umaric acid: From antioxidative and anti-inflammatory properties to effects on cell cycle and proliferation

MF Abazari, N Nasiri, SZ Karizi, F Nejati… - Mini reviews in …, 2021 - ingentaconnect.com
P-Coumaric acid (p-CA) is a hydroxycinnamic acid, an organic compound that is a hydroxyl
derivative of cinnamic acid. P-CA is the most abundant isomer in nature and can be found in …