The pH of the tumor microenvironment drives the metastatic phenotype and
chemotherapeutic resistance of tumors. Understanding the mechanisms underlying this pH …

Carbonic anhydrases are ubiquitous enzymes that catalyze the reversible hydration of
carbon dioxide. These enzymes are of ancient origin as they are found in the deepest of …

Background Dental caries is one of the most common chronic diseases and is influenced by
a complex interplay of genetic and environmental factors. Most previous genetic studies of …

Dental caries is a multifactorial chronic disease resulting from the intricate interplay among
acid‐generating bacteria, fermentable carbohydrates, and several host factors such as …

Визначено доцільність вивчення формування мікробних біоплівок на молочному
обладнанні. Виявлено, що на обладнанні утворюються біоплівки високої і середньої …

The microenvironment within a solid tumor is heterogeneous with regions being both acidic
and hypoxic. As a result of this, cancer cells upregulate genes that allow survival in such …

Aim This longitudinal study investigated the relationship among early childhood caries
(ECC), α amylase, carbonic anhydrase VI (CA VI), and the presence of visible biofilm …

Fifteen different carbonic anhydrase (CA) isoforms have been identified and characterized in
human (h) so far, of which 12 are catalytically active and 3 lack activity (CA-related proteins) …

Carbonic anhydrase VI (CA6) catalyses the reversible hydration of carbon dioxide in saliva
with possible pH regulation, taste perception, and tooth formation effects. This study …

Understanding proteins present in saliva and their function when isolated is not enough to
describe their real role in the mouth. Due to protein‐protein interactions, structural changes …