Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

Abstract Trypanosoma cruzi (Kinetoplastea: Trypanosomatidae) infects all tissues of its
hosts, which along with humans, include hundreds of mammalian species in the Americas …

Trypanosoma cruzi, the causative agent of Chagas disease, presents wide genetic diversity.
Currently, six discrete typing units (DTUs), named TcI to TcVI, and a seventh one called …

Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …

Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in
Central, South America, Mexico and the South of the United States. It is an important cause …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …