Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

CV Breton, R Landon, LG Kahn, MB Enlow… - Communications …, 2021 - nature.com
Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

DNA methylation markers in obesity, metabolic syndrome, and weight loss

M Samblas, FI Milagro, A Martínez - Epigenetics, 2019 - Taylor & Francis
The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …

Cell-type deconvolution from DNA methylation: a review of recent applications

AJ Titus, RM Gallimore, LA Salas… - Human molecular …, 2017 - academic.oup.com
Recent advances in cell-type deconvolution approaches are adding to our understanding of
the biology underlying disease development and progression. DNA methylation (DNAm) …

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

D Czamara, G Eraslan, CM Page, J Lahti… - Nature …, 2019 - nature.com
Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms
allowing integration of genetic and environmental factors to shape cellular function. While …

[HTML][HTML] Fetal programming of obesity and type 2 diabetes

SN Seneviratne, S Rajindrajith - World Journal of Diabetes, 2022 - ncbi.nlm.nih.gov
The prevalence of obesity and type 2 diabetes mellitus has increased rapidly over the past
few decades, and prevention efforts have not been successful. Fetal programming involves …

[HTML][HTML] Obesity in Pregnancy–Optimizing outcomes for mom and baby

HP Dutton, SJ Borengasser, LM Gaudet… - The Medical Clinics …, 2018 - pmc.ncbi.nlm.nih.gov
Obesity is common in women of childbearing age and management of this population
around the time of pregnancy involves specific challenges. Weight and medical …

Non-alcoholic fatty liver disease in obese youth with insulin resistance and type 2 diabetes

S Scapaticci, E D'Adamo, A Mohn, F Chiarelli… - Frontiers in …, 2021 - frontiersin.org
Currently, Non-Alcoholic Fatty Liver Disease (NAFLD) is the most prevalent form of chronic
liver disease in children and adolescents worldwide. Simultaneously to the epidemic …

A life history approach to the female sexual orientation spectrum: Evolution, development, causal mechanisms, and health

S Luoto, I Krams, MJ Rantala - Archives of Sexual Behavior, 2019 - Springer
Women's capacity for sexual fluidity is at least as interesting a phenomenon from the point of
view of evolutionary biology and behavioral endocrinology as exclusively homosexual …

Age at adiposity rebound in childhood is associated with PCOS diagnosis and obesity in adulthood—longitudinal analysis of BMI data from birth to age 46 in cases of …

E Koivuaho, J Laru, M Ojaniemi, K Puukka… - International journal of …, 2019 - nature.com
Abstract Background: Adiposity rebound (AR), the second BMI rise in childhood at around
the age of 6 years, is associated with obesity and metabolic alteration in later life. Given that …

[HTML][HTML] Recent advances in the application of a ketogenic diet for obesity management

N Drabińska, W Wiczkowski, MK Piskuła - Trends in Food Science & …, 2021 - Elsevier
Background In recent times, the prevalence of obesity increases, reaching an epidemic
scale. Elevated body weight is a risk factor in the development of several diseases such as …