Mast cells and basophils are potent effector cells of the innate immune system, and they
have both beneficial and detrimental functions for the host. They are mainly implicated in pro …

▪ Abstract When asthma is diagnosed, eosinophilic inflammation and airway remodeling are
established in the bronchial airways and can no longer be separated as cause and effect …

Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …

Professional phagocytes (such as macrophages) and non-professional phagocytes,,,,,,(such
as epithelial cells) clear billions of apoptotic cells and particles on a daily basis. Although …

Mast cells are known to be the main effector cells in the elicitation of the IgE‐mediated
allergic response. The specific location of mast cells within tissues that interface the external …

Mast cells (MC s) play a central role in tissue homoeostasis, sensing the local environment
through numerous innate cell surface receptors. This enables them to respond rapidly to …

Fibrosis is a medical condition characterized by an excessive deposition of extracellular
matrix compounds such as collagen in tissues. Fibrotic lesions are present in many diseases …

The ability of certain proteins to induce an allergic response in susceptible individuals is well
established. Symptoms can range from mild erythema or rhinitis, to acute, and possibly fatal …

The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …

Parasites are designed by evolution to invade the host and survive in its organism until they
are ready to reproduce. Parasites release a variety of molecules that help them to penetrate …