Northern Peru represents the center of the Andean “health axis,” with roots going back to
traditional practices of Cupisnique culture (1000 BC). For more than a decade of research …

The sesquiterpene p-benzoquinone perezone (1), isolated from Perezia adnata var. alamani
(Asteraceae), and its non-natural derivatives isoperezone (2), dihydroperezone (3) …

Respiratory tract infections continue to be a major health challenge worldwide especially
due to the increasingly fast development of resistance to the drugs currently in use. Many …

Several indolylquinone analogues of perezone, a natural sesquiterpene quinone, were
characterized in this work by theoretical methods. In addition, some physicochemical …

A series of eight amino derivatives (3a–h) from perezone 1 were prepared by nucleophilic
addition of bioactive amines v. gr. melatonin, acetyl tryptamine, tryptophan and other amino …

This invention relates to methods of extracting and purifying bioactive substances from
various plants and herbs. More speci? cally the invention relates to methods of extracting …

This chapter covers a sesquiterpene quinone, commonly named perezone. This molecule is
documented as the first secondary metabolite isolated in crystalline form in the New World in …

A green approach to produce the indolyl derivatives from four natural quinones (perezone,
isoperezone, menadione, and plumbagin) was performed; in this regard, a comparative …

Using DFT and in silico methods a theoretical study, to verify the spectroscopically
characterization, this in addition to determine the anti‐inflammatory activity of a set of eight …

Perezone had been used for centuries in the traditional Mexican medicine, it is useful and a
handful of illness. Perezone and other derivatives also present activity against certain lines …