The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

[HTML][HTML] Selenium and selenoproteins in viral infection with potential relevance to COVID-19

J Zhang, R Saad, EW Taylor, MP Rayman - Redox biology, 2020 - Elsevier
Selenium is a trace element essential to human health largely because of its incorporation
into selenoproteins that have a wide range of protective functions. Selenium has an ongoing …

Reductive stress in inflammation-associated diseases and the pro-oxidant effect of antioxidant agents

I Pérez-Torres, V Guarner-Lans… - International journal of …, 2017 - mdpi.com
Reductive stress (RS) is the counterpart oxidative stress (OS), and can occur in response to
conditions that shift the redox balance of important biological redox couples, such as the …

Chronic liver disease and oxidative stress–a narrative review

S Seen - Expert Review of Gastroenterology & Hepatology, 2021 - Taylor & Francis
Introduction: Oxidative stress underlies the pathophysiology of various etiologies of chronic
liver disease and contributes to the development of hepatocarcinogenesis. Areas covered …

[HTML][HTML] From liver fibrosis to hepatocarcinogenesis: Role of excessive liver H2O2 and targeting nanotherapeutics

M Shao, Y Wang, H Dong, L Wang, X Zhang, X Han… - Bioactive Materials, 2023 - Elsevier
Liver fibrosis and hepatocellular carcinoma (HCC) have been worldwide threats nowadays.
Liver fibrosis is reversible in early stages but will develop precancerosis of HCC in cirrhotic …

Emerging roles of peroxisomes in viral infections

AR Ferreira, M Marques, B Ramos, JC Kagan… - Trends in Cell …, 2022 - cell.com
Peroxisomes, essential subcellular organelles that fulfill important functions in lipid and
reactive oxygen species metabolism, have recently emerged as key players during viral …

Non-Alcoholic Fatty Liver Disease Is Associated with a Decreased Catalase (CAT) Level, CT Genotypes and the T Allele of the -262 C/T CAT Polymorphism

M Kosmalski, I Szymczak-Pajor, J Drzewoski… - Cells, 2023 - mdpi.com
Background: It is well known that oxidative stress plays an important role in the development
of non-alcoholic fatty liver disease (NAFLD). It has been suggested that an insufficient …

Organelle stress and alterations in interorganelle crosstalk during liver fibrosis

S Sinha, N Hassan, RE Schwartz - Hepatology, 2024 - journals.lww.com
The synchronous functioning and quality control of organelles ensure cell survival and
function and are essential for maintaining homeostasis. Prolonged exposure to stressors …

Association of GPx1 P198L and CAT C-262T Genetic Variations With Polycystic Ovary Syndrome in Chinese Women

Y Sun, S Li, H Liu, Y Gong, H Bai, W Huang… - Frontiers in …, 2019 - frontiersin.org
Background: Oxidative stress plays an important role in the pathogenesis of polycystic ovary
syndrome (PCOS). Glutathione peroxidase 1 (GPx1) and catalase (CAT) are the major …

[HTML][HTML] Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 …

K Liu, X Liu, M Wang, X Wang, H Kang, S Lin, P Yang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies have focused on the associations of catalase polymorphisms with various
types of cancer, including cervical and prostate cancers. However, the results were …