Chemokines are small secretory chemotactic cytokines that control the directed migration of
immune cells. Chemokines are involved in both anti-and pro-tumorigenic immune …

Cancer cells exist in a complex ecosystem with numerous other cell types in the tumor
microenvironment (TME). The composition of this tumor/TME ecosystem will vary at each …

The cost of antitumor drug development is enormous, yet the clinical outcomes are less than
satisfactory. Therefore, it is of great importance to develop effective drug screening methods …

Despite billions of dollars invested into cancer drug development each year, studies have
shown that oncological clinical trials had a staggeringly low success rate of 3.5% in 2022 [1] …

Objective A visual metastasis model of hepatoma cells and cancer-associated fibroblasts
(CAFs) was established using zebrafish to provide a preclinical model for CAFs-mediated …

Cancer is the second highest cause of death globally. In an estimated 90% of all cases, the
spread of cancer cells from the initial tumor to a distant site—aka metastasis—is the primary …