Cerebrospinal fluid shunting complications in children
Although cerebrospinal fluid (CSF) shunt placement is the most common procedure
performed by pediatric neurosurgeons, shunts remain among the most failure-prone life …
performed by pediatric neurosurgeons, shunts remain among the most failure-prone life …
Cerebrospinal fluid shunt malfunctions: A reflective review
SYY Low, JRW Kestle, ML Walker, WT Seow - Child's Nervous System, 2023 - Springer
Purpose Pediatric hydrocephalus is a common and challenging condition. To date, the
ventriculoperitoneal shunt (VPS) is still the main lifesaving treatment option. Nonetheless, it …
ventriculoperitoneal shunt (VPS) is still the main lifesaving treatment option. Nonetheless, it …
Shunt-dependent hydrocephalus: management style among members of the American Society of Pediatric Neurosurgeons
MR Kraemer, C Sandoval-Garcia, T Bragg… - Journal of …, 2017 - thejns.org
OBJECTIVE The authors conducted a survey to evaluate differences in the understanding
and management of shunt-dependent hydrocephalus among members of the American …
and management of shunt-dependent hydrocephalus among members of the American …
A multicenter retrospective study of heterogeneous tissue aggregates obstructing ventricular catheters explanted from patients with hydrocephalus
P Hariharan, J Sondheimer, A Petroj, J Gluski… - Fluids and Barriers of …, 2021 - Springer
Background Implantation of ventricular catheters (VCs) to drain cerebrospinal fluid (CSF) is
a standard approach to treat hydrocephalus. VCs fail frequently due to tissue obstructing the …
a standard approach to treat hydrocephalus. VCs fail frequently due to tissue obstructing the …
Toward a better understanding of the cellular basis for cerebrospinal fluid shunt obstruction: report on the construction of a bank of explanted hydrocephalus devices
OBJECTIVE Shunt obstruction by cells and/or tissue is the most common cause of shunt
failure. Ventricular catheter obstruction alone accounts for more than 50% of shunt failures in …
failure. Ventricular catheter obstruction alone accounts for more than 50% of shunt failures in …
Reduced cell attachment to poly(2‐hydroxyethyl methacrylate)‐coated ventricular catheters in vitro
The majority of patients with hydrocephalus are dependent on ventriculoperitoneal shunts
for diversion of excess cerebrospinal fluid. Unfortunately, these shunts are failure‐prone and …
for diversion of excess cerebrospinal fluid. Unfortunately, these shunts are failure‐prone and …
An astrocyte derived extracellular matrix coating reduces astrogliosis surrounding chronically implanted microelectrode arrays in rat cortex
Available evidence suggests that the magnitude of the foreign body response (FBR) to
implants placed in cortical brain tissue is affected by the extent of vasculature damage …
implants placed in cortical brain tissue is affected by the extent of vasculature damage …
Characterization of a multicenter pediatric-hydrocephalus shunt biobank
J Gluski, P Zajciw, P Hariharan, A Morgan… - Fluids and Barriers of …, 2020 - Springer
Background Pediatric hydrocephalus is a devastating and costly disease. The mainstay of
treatment is still surgical shunting of cerebrospinal fluid (CSF). These shunts fail at a high …
treatment is still surgical shunting of cerebrospinal fluid (CSF). These shunts fail at a high …
Exploration of clinical predictors of the degree of ventricular catheter obstruction: a multicenter retrospective study
P Hariharan, J Gluski, J Sondheimer, A Petroj… - Journal of …, 2023 - thejns.org
OBJECTIVE The aim of this study was to explore how clinical factors, including the number
of lifetime revision surgeries and the duration of implantation, affect the degree of obstruction …
of lifetime revision surgeries and the duration of implantation, affect the degree of obstruction …
Enhanced wall shear stress prevents obstruction by astrocytes in ventricular catheters
S Lee, N Kwok, J Holsapple… - Journal of the Royal …, 2020 - royalsocietypublishing.org
The treatment of hydrocephalus often involves the placement of a shunt catheter into the
cerebrospinal ventricular space, though such ventricular catheters often fail by tissue …
cerebrospinal ventricular space, though such ventricular catheters often fail by tissue …