Progestins as endocrine disrupters in aquatic ecosystems: concentrations, effects and risk assessment

K Fent - Environment international, 2015 - Elsevier
In aquatic ecosystems, progesterone (P4) and synthetic progestins (gestagens) originate
from excretion by humans and livestock. Synthetic progestins are used for contraception and …

The challenge presented by progestins in ecotoxicological research: a critical review

V Kumar, AC Johnson, A Trubiroha… - … science & technology, 2015 - ACS Publications
Around 20 progestins (also called gestagens, progestogens, or progestagens) are used
today in assisting a range of medical conditions from endometrial cancer to uterine bleeding …

Improving environmental risk assessment of human pharmaceuticals

M Ågerstrand, C Berg, B Björlenius… - Environmental …, 2015 - ACS Publications
This paper presents 10 recommendations for improving the European Medicines Agency's
guidance for environmental risk assessment of human pharmaceutical products. The …

Several synthetic progestins with different potencies adversely affect reproduction of fish

TJ Runnalls, N Beresford, E Losty… - … science & technology, 2013 - ACS Publications
Synthetic progestins are widely used as a component in both contraceptives and in hormone
replacement therapy (HRT), both on their own and in combination with EE2. Their presence …

Prioritising pharmaceuticals for environmental risk assessment: towards adequate and feasible first-tier selection

V Roos, L Gunnarsson, J Fick, DGJ Larsson… - Science of the Total …, 2012 - Elsevier
The presence of pharmaceuticals in the aquatic environment, and the concerns for negative
effects on aquatic organisms, has gained increasing attention over the last years. As …

Pharmaceutical residues in sewage sludge: Effect of sanitization and anaerobic digestion

J Malmborg, J Magnér - Journal of environmental management, 2015 - Elsevier
The fate of pharmaceutical residues in treatment of WWTP sludge was evaluated during
mesophilic anaerobic digestion (AD) and six sanitization technologies (pasteurization …

Determination and characterization of pharmaceuticals in sludge from municipal and livestock wastewater treatment plants

KI Ekpeghere, JW Lee, HY Kim, SK Shin, JE Oh - Chemosphere, 2017 - Elsevier
This study investigated 24 pharmaceuticals compounds belonging to the classes of
analgesics, stimulants, anti-seizures, non-steroidal anti-inflammatory drugs (NSAIDs), and …

Do hormone‐modulating chemicals impact on reproduction and development of wild amphibians?

F Orton, CR Tyler - Biological Reviews, 2015 - Wiley Online Library
Globally, amphibians are undergoing a precipitous decline. At the last estimate in 2004,
32% of the approximately 6000 species were threatened with extinction and 43% were …

Agrochemicals disrupt multiple endocrine axes in amphibians

VL Trudeau, P Thomson, WS Zhang, S Reynaud… - Molecular and cellular …, 2020 - Elsevier
Concern over global amphibian declines and possible links to agrochemical use has led to
research on the endocrine disrupting actions of agrochemicals, such as fertilizers …

[PDF][PDF] Pharmaceutical waste management an overview

A Kadam, S Patil, S Patil, A Tumkur - Indian Journal of Pharmacy …, 2016 - researchgate.net
Introduction: Medication disposal is an alarming issue today and gaining more and more
awareness from the healthcare professionals as well as consumers. Pharmacists have the …