Key determinants for the development of an allergic response to an otherwise 'harmless'
food protein involve different factors like the predisposition of the individual, the timing, the …

This review focuses on advances and updates in the epidemiology, pathogenesis,
diagnosis, and treatment of food allergy over the past 3 years since our last comprehensive …

The improvement of the knowledge of the pathophysiological mechanisms underlying the
tolerance and sensitization to food antigens has recently led to a radical change in the …

Environmentally induced alterations in the commensal microbiota have been implicated in
the increasing prevalence of food allergy. We show here that sensitization to a food allergen …

Background Exposure to food allergens through a disrupted skin barrier has been
recognized as a potential factor in the increasing prevalence of food allergy. Objective We …

Background Cutaneous exposure to food allergens predisposes to food allergy, which is
commonly associated with atopic dermatitis (AD). Levels of the epithelial cytokine IL-33 are …

A polymorphism in the autophagy gene Atg16l1 is associated with susceptibility to
inflammatory bowel disease (IBD); however, it remains unclear how autophagy contributes …

Eosinophils natively inhabit the small intestine, but a functional role for them there has
remained elusive. Here, we show that eosinophil-deficient mice were protected from …

Food allergy is a significant issue worldwide, particularly in Westernised countries. There is
no clear explanation why food allergy appears to have increased so rapidly in recent years …

Background A number of food allergies (eg, fish, shellfish, and nuts) are lifelong, without any
disease-transforming therapies, and unclear in their underlying immunology. Clinical …