Background Asia consists of diverse nations with extremely variable health care systems.
Integrated real-world data (RWD) research warehouses provide vast interconnected data …

Objective We aimed to describe the following in patients with polymyalgia rheumatica
(PMR):(1) real-world glucocorticoid (GC) therapy,(2) improvement in inflammatory …

Background Evidence is lacking on the association between antibiotic use and risk of
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Asians. Objective …

Background When considering changing hypnotic pharmacotherapy, lemborexant has
attracted attention as a candidate due to its effectiveness and safety profile. However, few …

Objective: To investigate the association between atomoxetine or methylphenidate use and
arrhythmia, heart failure (HF), stroke, and myocardial infarction (MI) in attention …

Introduction A safety signal concerning parkinsonism and related movement disorders with
gabapentinoids (gabapentin and pregabalin) or tramadol was detected by reviewing …

Background: The effectiveness and safety of edoxaban for venous thromboembolism (VTE)
in unselected real-world patients have not been fully evaluated. Methods and Results: In the …

Although some case reports have reported gastrointestinal perforation after COVID-19,
epidemiological studies investigating this association are scarce. We aimed to assess the …

Objectives The diagnosis of early‐onset Alzheimer's disease (EOAD) can cause emotional
stress not only to the patients themselves but also to their spouses. This study aimed to …

Background Moyamoya disease (MMD) is characterized by progressive stenosis or
occlusion of the terminal portions of the bilateral internal carotid arteries. A Japanese survey …