[HTML][HTML] Engineering aortic valves via transdifferentiating fibroblasts into valvular endothelial cells without using viruses or iPS cells

P Tang, F Wei, W Qiao, X Chen, C Ji, W Yang… - Bioactive Materials, 2025 - Elsevier
The technology of induced pluripotent stem cells (iPSCs) has enabled the conversion of
somatic cells into primitive undifferentiated cells via reprogramming. This approach provides …

Nano‐Biosensors for mRNA‐Based Cell Sorting Using Intracellular Markers at the Early Stage of Cell Reprogramming

Y Song, J Soto, X Lin, T Hoffman, E Hu… - Advanced Functional …, 2024 - Wiley Online Library
Cell reprogramming and manufacturing have broad applications in tissue regeneration and
disease treatment. However, many derived cell types lack unique cell surface markers for …

T Cells Spatially Regulate B Cell Receptor Signaling in Lymphomas through H3K9me3 Modifications

LS Britto, D Balasubramani, S Desai… - Advanced …, 2024 - Wiley Online Library
Activated B cell‐like diffuse large B‐cell lymphoma (ABC‐DLBCL) is a subtype associated
with poor survival outcomes. Despite identifying therapeutic targets through molecular …

Polymer Model Integrates Super-Resolution Imaging and Epigenomic Sequencing to Elucidate the Role of Epigenetic Reactions in Shaping 4D Chromatin …

V Vinayak, R Basir, R Golloshi, JM Toth, L Sant'Anna… - bioRxiv, 2024 - biorxiv.org
Chromatin, with its complex spatial and temporal organization, plays a crucial role in
regulating gene expression. Recent advancements in super-resolution microscopy have …

Design and Fabrication of Viscoelastic Hydrogels as Extracellular Matrix Mimicry for Cell Engineering

ZY Li, TY Li, HC Yang, MH Ding, LJ Chen… - Chem & Bio …, 2024 - ACS Publications
The extracellular matrix (ECM) performs both as a static scaffold and as a dynamic,
viscoelastic milieu that actively participates in cell signaling and mechanical feedback loops …