Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance
S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …
as nuclei of great value for obtaining molecules with various biological activities, including …
Thiazoles and thiazolidinones as COX/LOX inhibitors
K Liaras, M Fesatidou, A Geronikaki - Molecules, 2018 - mdpi.com
Inflammation is a natural process that is connected to various conditions and disorders such
as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase …
as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase …
Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif
The acetylcholinesterase and carbonic anhydrase inhibitors (AChEIs and h CAIs) remain
key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity …
key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity …
Multicomponent reaction for the synthesis of new 1, 3, 4-thiadiazole-thiazolidine-4-one molecular hybrids as promising antidiabetic agents through α-glucosidase and …
A simple and efficient protocol was developed to synthesize a new library of thiazolidine-4-
one molecular hybrids (4a-n) via a one-pot multicomponent reaction involving 5-substituted …
one molecular hybrids (4a-n) via a one-pot multicomponent reaction involving 5-substituted …
Design and synthesis of some novel hybrid molecules based on 4-thiazolidinone bearing pyridine-pyrazole scaffolds: molecular docking and molecular dynamics …
Due to multidrug resistance, microbial infections have become significant on a global level.
As infections caused by several resistant bacteria and fungi severely harm mankind …
As infections caused by several resistant bacteria and fungi severely harm mankind …
Design, synthesis, antimicrobial evaluation, and molecular docking study of some 4-thiazolidinone derivatives containing pyridine and quinazoline moiety
NC Desai, KA Jadeja, DJ Jadeja… - Synthetic …, 2021 - Taylor & Francis
Abstract A series of 5-aryl-3-(4-oxo-2-phenylquinazolin-3 (4 H)-yl)-2-(pyridin-4-yl) thiazolidin-
4-ones were synthesized and evaluated for their antibacterial and antifungal activities …
4-ones were synthesized and evaluated for their antibacterial and antifungal activities …
Molecular docking studies of HIV-1 resistance to reverse transcriptase inhibitors: mini-review
O Tarasova, V Poroikov, A Veselovsky - Molecules, 2018 - mdpi.com
Currently, millions of people are living with human immunodeficiency virus type 1 (HIV-1),
which causes acquired immunodeficiency syndrome. However, the spread of the HIV-1 …
which causes acquired immunodeficiency syndrome. However, the spread of the HIV-1 …
Heterocycle compounds with antimicrobial activity
M Fesatidou, A Petrou, G Athina - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Bacterial infections are a growing problem worldwide causing morbidity and
mortality mainly in developing countries. Moreover, the increased number of …
mortality mainly in developing countries. Moreover, the increased number of …
Thiazolidin-4-one-based derivatives–Efficient tools for designing antiprotozoal agents. A review of the last decade
H Tuszewska, J Szczepański, S Mandziuk… - Bioorganic Chemistry, 2023 - Elsevier
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …
Discovery of N-Phenylaminomethylthioacetylpyrimidine-2,4-diones as Protoporphyrinogen IX Oxidase Inhibitors through a Reaction Intermediate Derivation …
DW Wang, L Liang, ZY Xue, SY Yu… - Journal of Agricultural …, 2021 - ACS Publications
Protoporphyrinogen oxidase (PPO, EC 1.3. 3.4) is an effective target for green herbicide
discovery. In this work, we reported the unexpected discovery of a novel series of N …
discovery. In this work, we reported the unexpected discovery of a novel series of N …