Yarrowia lipolytica Strains and Their Biotechnological Applications: How Natural Biodiversity and Metabolic Engineering Could Contribute to Cell Factories …

C Madzak - Journal of Fungi, 2021 - mdpi.com
Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …

Metabolic engineering in the host Yarrowia lipolytica

AM Abdel-Mawgoud, KA Markham, CM Palmer… - Metabolic …, 2018 - Elsevier
The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …

Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering

ML Sun, TQ Shi, L Lin, R Ledesma-Amaro, XJ Ji - Bioresource Technology, 2022 - Elsevier
Yarrowia lipolytica is recognized as an excellent non-conventional yeast in the field of
biomanufacturing, where it is used as a host to produce oleochemicals, terpenes, organic …

Oleaginous yeast for biofuel and oleochemical production

M Spagnuolo, A Yaguchi, M Blenner - Current Opinion in Biotechnology, 2019 - Elsevier
Highlights•The yeasts, Cutaneotrichosporon oleaginosus, Lipomyces starkeyi, and
Rhodosporidium toruloides, grow on a wide range of substrates and naturally outperform …

Synthetic biology expands the industrial potential of Yarrowia lipolytica

KA Markham, HS Alper - Trends in biotechnology, 2018 - cell.com
The oleaginous yeast Yarrowia lipolytica is quickly emerging as the most popular non-
conventional (ie, non-model organism) yeast in the bioproduction field. With a high …

Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield

Y Lv, Y Gu, J Xu, J Zhou, P Xu - Metabolic engineering, 2020 - Elsevier
Metabolic addiction, an organism that is metabolically addicted with a compound to maintain
its growth fitness, is an underexplored area in metabolic engineering. Microbes with heavily …

Recent advances in lipid metabolic engineering of oleaginous yeasts

A Chattopadhyay, M Mitra, MK Maiti - Biotechnology Advances, 2021 - Elsevier
With the increasing demand to develop a renewable and sustainable biolipid feedstock,
several species of non-conventional oleaginous yeasts are being explored. Apart from the …

Alternative Substrate Metabolism in Yarrowia lipolytica

M Spagnuolo, M Shabbir Hussain, L Gambill… - Frontiers in …, 2018 - frontiersin.org
Recent advances in genetic engineering capabilities have enabled the development of
oleochemical producing strains of Yarrowia lipolytica. Much of the metabolic engineering …

Obscure yet promising oleaginous yeasts for fuel and chemical production

RV Sreeharsha, SV Mohan - Trends in biotechnology, 2020 - cell.com
The rapid depletion of petroleum-based fossil fuels has led to the development of alternative
fuel and energy solutions from renewable resources. Lipid-derived oleochemicals and sugar …

Promoter engineering strategies for the overproduction of valuable metabolites in microbes

LQ Jin, WR Jin, ZC Ma, Q Shen, X Cai, ZQ Liu… - Applied Microbiology …, 2019 - Springer
Promoter engineering is an enabling technology in metabolic engineering and synthetic
biology. As an indispensable part of synthetic biology, the promoter is a key factor in …