The astounding world of glycans from giant viruses

I Speciale, A Notaro, C Abergel, R Lanzetta… - Chemical …, 2022 - ACS Publications
Viruses are a heterogeneous ensemble of entities, all sharing the need for a suitable host to
replicate. They are extremely diverse, varying in morphology, size, nature, and complexity of …

[HTML][HTML] Chloroviruses

JL Van Etten, IV Agarkova, DD Dunigan - Viruses, 2019 - mdpi.com
Chloroviruses are large dsDNA, plaque-forming viruses that infect certain chlorella-like
green algae; the algae are normally mutualistic endosymbionts of protists and metazoans …

Synthesis of N‐Glycosides by Silver‐Assisted Gold Catalysis

S Chakraborty, B Mishra, P Kumar Das… - Angewandte Chemie …, 2023 - Wiley Online Library
The synthesis of N‐glycosides from stable glycosyl donors in a catalytic fashion is still
challenging, though they exist ubiquitously in DNA, RNA, glycoproteins, and other biological …

NEGATIVE ION MASS SPECTROMETRY FOR THE ANALYSIS OF N‐LINKED GLYCANS

DJ Harvey - Mass Spectrometry Reviews, 2020 - Wiley Online Library
N‐glycans from glycoproteins are complex, branched structures whose structural
determination presents many analytical problems. Mass spectrometry, usually conducted in …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2015–2016

DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

[HTML][HTML] Chloroviruses have a sweet tooth

JL Van Etten, I Agarkova, DD Dunigan, M Tonetti… - Viruses, 2017 - mdpi.com
Chloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of
chlorella-like green algae. They contain up to approximately 400 protein-encoding genes …

Structure of the chlorovirus PBCV-1 major capsid glycoprotein determined by combining crystallographic and carbohydrate molecular modeling approaches

C De Castro, T Klose, I Speciale… - Proceedings of the …, 2018 - National Acad Sciences
The glycans of the major capsid protein (Vp54) of Paramecium bursaria chlorella virus
(PBCV-1) were recently described and found to be unusual. This prompted a reexamination …

Giant viruses of the Megavirinae subfamily possess biosynthetic pathways to produce rare bacterial-like sugars in a clade-specific manner

A Notaro, O Poirot, ED Garcin, S Nin, A Molinaro… - …, 2022 - academic.oup.com
The recent discovery that giant viruses encode proteins related to sugar synthesis and
processing paved the way for the study of their glycosylation machinery. We focused on the …

[HTML][HTML] The autonomous glycosylation of large DNA viruses

F Piacente, M Gaglianone, ME Laugieri… - International Journal of …, 2015 - mdpi.com
Glycosylation of surface molecules is a key feature of several eukaryotic viruses, which use
the host endoplasmic reticulum/Golgi apparatus to add carbohydrates to their nascent …

Expanding the occurrence of polysaccharides to the viral world: the case of Mimivirus

A Notaro, Y Couté, L Belmudes… - Angewandte Chemie …, 2021 - Wiley Online Library
The general perception of viruses is that they are small in terms of size and genome, and
that they hijack the host machinery to glycosylate their capsid. Giant viruses subvert all these …