Frailty is a distinctive health state in which the ability of older people to cope with acute
stressors is compromised by an increased vulnerability brought by age-associated declines …

Abstract Purpose of Review To summarise evidence on both appropriate and inappropriate
antihypertensive drug withdrawal. Recent Findings Deprescribing should be attempted in …

Hypertension is a frequent finding in elderly patients. Hypertension in older age can be both
associated with frailty and represent a risk factor for frailty. Hypertension is recognized as a …

Background Blood pressure (BP) management in frail older people is challenging. An
randomised controlled trial of largely non-frail older people found cardiovascular and …

Current evidence is insufficient to support different hypertension treatment targets in older
adults. We evaluated whether frailty modifies the association between systolic blood …

BACKGROUND/OBJECTIVES Randomized controlled trials are used to inform clinical
guidelines on the management of hypertension in older adults, but it is unclear to what …

Hypertension management forms a cornerstone of cardiovascular prevention. Strong
evidence is available supporting the benefits of blood pressure (BP) lowering in older adults …

Objectives: Hypertension is highly prevalent in the elderly and represents a major risk factor
for cardiovascular complications such as coronary heart disease, stroke, and cognitive …

Objective. Chronological age alone does not adequately reflect the difference in health
status of a patient with hypertension. Frailty is closely associated with biological age, and its …

Background The relationship between hypertension and cognition in later life is
controversial. We investigated whether the association of hypertension with cognition differs …