Neuronal ganglioside and glycosphingolipid (GSL) metabolism and disease: cascades of secondary metabolic errors can generate complex pathologies (in LSDs)
R Sandhoff, K Sandhoff - Glycobiology of the Nervous System, 2022 - Springer
Glycosphingolipids (GSLs) are a diverse group of membrane components occurring mainly
on the surfaces of mammalian cells. They and their metabolites have a role in intercellular …
on the surfaces of mammalian cells. They and their metabolites have a role in intercellular …
Adipokines, Vitamin D, and Selected Inflammatory Biomarkers among Parkinson's Disease Patients with and without Dyskinesia: A Preliminary Examination
J Milanowski, J Nuszkiewicz, B Lisewska, P Lisewski… - Metabolites, 2024 - mdpi.com
Parkinson's disease (PD), a widely recognized neurodegenerative disorder, is characterized
by a spectrum of symptoms including motor fluctuations and dyskinesia. Neuroinflammation …
by a spectrum of symptoms including motor fluctuations and dyskinesia. Neuroinflammation …
[HTML][HTML] Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation
Mutations in the granulin (GRN) gene, resulting in haploinsufficiency of the progranulin
(PGRN) protein, are a leading cause of frontotemporal lobar degeneration (FTLD) and …
(PGRN) protein, are a leading cause of frontotemporal lobar degeneration (FTLD) and …
The sphingolipid asset is altered in the nigrostriatal system of mice models of Parkinson's disease
V Blokhin, M Shupik, U Gutner, E Pavlova, AT Lebedev… - Biomolecules, 2022 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disease incurable due to late diagnosis
and treatment. Therefore, one of the priorities of neurology is to study the mechanisms of PD …
and treatment. Therefore, one of the priorities of neurology is to study the mechanisms of PD …
CB2, PPAR-γ and GPR55 as pharmacological targets for an anti-inflammatory and neuroprotective treatment of Parkinson's disease
S Burgaz García-Oteyza - 2023 - docta.ucm.es
Parkinson's disease (PD) is a chronic neurodegenerative disorder which courses with
hypokinetic symptoms due to the selective death of the dopaminergic neurons of the …
hypokinetic symptoms due to the selective death of the dopaminergic neurons of the …