The probabilistic model of Alzheimer disease: the amyloid hypothesis revised
The current conceptualization of Alzheimer disease (AD) is driven by the amyloid
hypothesis, in which a deterministic chain of events leads from amyloid deposition and then …
hypothesis, in which a deterministic chain of events leads from amyloid deposition and then …
Global prevalence of young-onset dementia: a systematic review and meta-analysis
S Hendriks, K Peetoom, C Bakker… - JAMA …, 2021 - jamanetwork.com
Importance Reliable prevalence estimates are lacking for young-onset dementia (YOD), in
which symptoms of dementia start before the age of 65 years. Such estimates are needed for …
which symptoms of dementia start before the age of 65 years. Such estimates are needed for …
The role of reactive oxygen species in the pathogenesis of Alzheimer's disease, Parkinson's disease, and Huntington's disease: a mini review
S Manoharan, GJ Guillemin… - Oxidative medicine …, 2016 - Wiley Online Library
Neurodegenerative diseases affect not only the life quality of aging populations, but also
their life spans. All forms of neurodegenerative diseases have a massive impact on the …
their life spans. All forms of neurodegenerative diseases have a massive impact on the …
Dementia: timely diagnosis and early intervention
Dementia describes a clinical syndrome that encompasses difficulties in memory, language,
and behaviour that leads to impairments in activities of daily living. Alzheimer's disease is …
and behaviour that leads to impairments in activities of daily living. Alzheimer's disease is …
[HTML][HTML] Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study
Background There is need to identify targets for preventing or delaying dementia. Social
contact is a potential target for clinical and public health studies, but previous observational …
contact is a potential target for clinical and public health studies, but previous observational …
The prevalence and incidence of frontotemporal dementia: a systematic review
BackgroundPopulation-based prevalence and incidence studies are essential for
understanding the burden of frontotemporal dementia (FTD). MethodsThe MEDLINE and …
understanding the burden of frontotemporal dementia (FTD). MethodsThe MEDLINE and …
[HTML][HTML] Epidemiology of early-onset dementia: a review of the literature
Abstract Presenile Dementia or Early Onset Dementia (EOD) is a public health problem, it
differs from Senile Dementia, and encloses a significant number of cases; nevertheless, it is …
differs from Senile Dementia, and encloses a significant number of cases; nevertheless, it is …
[HTML][HTML] Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort
E Shishtar, GT Rogers, JB Blumberg, R Au… - The American journal of …, 2020 - Elsevier
Background Findings from existing prospective observational studies on the protective
associations of flavonoid intake and the risk of Alzheimer disease and related dementias …
associations of flavonoid intake and the risk of Alzheimer disease and related dementias …
Genetics of dementia
Summary 25% of all people aged 55 years and older have a family history of dementia. For
most, the family history is due to genetically complex disease, where many genetic …
most, the family history is due to genetically complex disease, where many genetic …
Relationship between cortical iron and tau aggregation in Alzheimer's disease
N Spotorno, J Acosta-Cabronero, E Stomrud… - Brain, 2020 - academic.oup.com
A growing body of evidence suggests that the dysregulation of neuronal iron may play a
critical role in Alzheimer's disease. Recent MRI studies have established a relationship …
critical role in Alzheimer's disease. Recent MRI studies have established a relationship …