Trace amines and their receptors

RR Gainetdinov, MC Hoener, MD Berry - Pharmacological reviews, 2018 - ASPET
Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Therapeutic potential of TAAR1 agonists in schizophrenia: evidence from preclinical models and clinical studies

N Dedic, H Dworak, C Zeni, G Rutigliano… - International Journal of …, 2021 - mdpi.com
Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …

ADHD: Reviewing the causes and evaluating solutions

L Núñez-Jaramillo, A Herrera-Solís… - Journal of personalized …, 2021 - mdpi.com
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder in which
patients present inattention, hyperactivity, and impulsivity. The etiology of this condition is …

Measuring behavior in the home cage: study design, applications, challenges, and perspectives

F Grieco, BJ Bernstein, B Biemans… - Frontiers in behavioral …, 2021 - frontiersin.org
The reproducibility crisis (or replication crisis) in biomedical research is a particularly
existential and under-addressed issue in the field of behavioral neuroscience, where, in …

Experience during adolescence shapes brain development: From synapses and networks to normal and pathological behavior

D Dow-Edwards, FP MacMaster, BS Peterson… - Neurotoxicology and …, 2019 - Elsevier
Adolescence is a period of dramatic neural reorganization creating a period of vulnerability
and the possibility for the development of psychopathology. The maturation of various neural …

The development of compulsive coping behavior depends on dorsolateral striatum dopamine-dependent mechanisms

L Marti-Prats, C Giuliano, A Domi, M Puaud… - Molecular …, 2023 - nature.com
Humans greatly differ in how they cope with stress, a natural behavior learnt through
negative reinforcement. Some individuals engage in displacement activities, others in …

Behavioral phenotyping of dopamine transporter knockout rats: compulsive traits, motor stereotypies, and anhedonia

S Cinque, F Zoratto, A Poleggi, D Leo… - Frontiers in …, 2018 - frontiersin.org
Alterations in dopamine neurotransmission are generally associated with diseases such as
attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) …

Dopamine, erectile function and male sexual behavior from the past to the present: a review

MR Melis, F Sanna, A Argiolas - Brain Sciences, 2022 - mdpi.com
Early and recent studies show that dopamine through its neuronal systems and receptor
subtypes plays different roles in the control of male sexual behavior. These studies show …

Dopamine transporter silencing in the rat: systems-level alterations in striato-cerebellar and prefrontal-midbrain circuits

JR Reinwald, N Gass, AS Mallien, A Sartorius… - Molecular …, 2022 - nature.com
Silencing of dopamine transporter (DAT), a main controlling factor of dopaminergic
signaling, results in biochemical and behavioral features characteristic for neuropsychiatric …

Persistent binding at dopamine transporters determines sustained psychostimulant effects

M Niello, S Sideromenos, R Gradisch… - Proceedings of the …, 2023 - National Acad Sciences
Psychostimulants interacting with the dopamine transporter (DAT) can be used illicitly or for
the treatment of specific neuropsychiatric disorders. However, they can also produce severe …