Live-attenuated vaccines (LAVs) can protect humans against 12 viral and three bacterial
diseases. By definition, any clinical infection caused by a LAV that is sufficiently severe to …

Rotavirus is a leading cause of severe dehydrating diarrhoea in infants and young children.
Following rotavirus infection in the intestine an innate immune response is rapidly triggered …

Type I IFNs are key cytokines mediating innate antiviral immunity. cGMP-AMP synthase,
ritinoic acid-inducible protein 1 (RIG-I)–like receptors, and Toll-like receptors recognize …

Rotavirus (RV) infection is one of the main pathogenic causes of severe gastroenteritis and
diarrhea in infants and young animals. This study aimed to determine how dietary l …

In this work, we aimed to characterize the antiviral response of an originally established
porcine intestinal epithelial cell line (PIE cells) by evaluating the molecular innate immune …

Rotavirus (RV) replicates efficiently in intestinal epithelial cells (IECs) in vivo despite the
activation of a local host interferon (IFN) response. Previously, we demonstrated that …

Rotaviruses (RVs) are the leading cause of severe gastroenteritis in young children,
accounting for half a million deaths annually worldwide. RV encodes non-structural protein 1 …

Persistent human papillomavirus (HPV) infections is necessary for the development of
cervical cancers. An increasing number of retrospective studies have found the depletion of …

The mammalian interferon (IFN) signaling pathway is a primary component of the innate
antiviral response, and viral pathogens have evolved multiple mechanisms to antagonize …

Rotavirus is a leading cause of death due to diarrhea among young children across the
globe. Despite the limited coding capacity that is characteristic of RNA viruses, rotavirus …