[HTML][HTML] Current insights into the bone marrow niche: From biology in vivo to bioengineering ex vivo
Y Xiao, CAS McGuinness, WS Doherty-Boyd… - Biomaterials, 2022 - Elsevier
Hematopoietic stem cells (HSCs) are fundamental to the generation of the body's blood and
immune cells. They reside primarily within the bone marrow (BM) niche microenvironment …
immune cells. They reside primarily within the bone marrow (BM) niche microenvironment …
Hydrogels for large-scale expansion of stem cells
S Yin, Y Cao - Acta biomaterialia, 2021 - Elsevier
Stem cells demonstrate considerable promise for various preclinical and clinical
applications, including drug screening, disease treatments, and regenerative medicine …
applications, including drug screening, disease treatments, and regenerative medicine …
The use of covalently immobilized stem cell factor to selectively affect hematopoietic stem cell activity within a gelatin hydrogel
Hematopoietic stem cells (HSCs) are a rare stem cell population found primarily in the bone
marrow and responsible for the production of the body's full complement of blood and …
marrow and responsible for the production of the body's full complement of blood and …
Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science
Hematopoietic stem cells (HSCs) play a crucial role in the generation of the body's blood
and immune cells. This process takes place primarily in the bone marrow in …
and immune cells. This process takes place primarily in the bone marrow in …
Soluble signals and remodeling in a synthetic gelatin‐based hematopoietic stem cell niche
Hematopoietic stem cells (HSCs) reside in the bone marrow within niches that provide
microenvironmental signals in the form of biophysical cues, bound and diffusible …
microenvironmental signals in the form of biophysical cues, bound and diffusible …
The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment
S Klamer, C Voermans - Cell adhesion & migration, 2014 - Taylor & Francis
Maintenance of haematopoietic stem cells and differentiation of committed progenitors
occurs in highly specialized niches. The interactions of haematopoietic stem and progenitor …
occurs in highly specialized niches. The interactions of haematopoietic stem and progenitor …
Current approaches in biomaterial-based hematopoietic stem cell niches
Hematopoietic stem cells (HSCs) are multipotent progenitor cells that can differentiate and
replenish blood and immune cells. While there is a growing demand for autologous and …
replenish blood and immune cells. While there is a growing demand for autologous and …
Immobilization of growth factors for cell therapy manufacturing
D Enriquez-Ochoa, P Robles-Ovalle… - … in bioengineering and …, 2020 - frontiersin.org
Cell therapy products exhibit great therapeutic potential but come with a deterring price tag
partly caused by their costly manufacturing processes. The development of strategies that …
partly caused by their costly manufacturing processes. The development of strategies that …
The influence of hyaluronic acid and glioblastoma cell coculture on the formation of endothelial cell networks in gelatin hydrogels
Glioblastoma (GBM) is the most common and deadly form of brain cancer. Interactions
between GBM cells and vasculature in vivo contribute to poor clinical outcomes, with GBM …
between GBM cells and vasculature in vivo contribute to poor clinical outcomes, with GBM …
Administration of signalling molecules dictates stem cell homing for in situ regeneration
X Li, XT He, Y Yin, RX Wu, BM Tian… - Journal of Cellular and …, 2017 - Wiley Online Library
Ex vivo‐expanded stem cells have long been a cornerstone of biotherapeutics and have
attracted increasing attention for treating intractable diseases and improving tissue …
attracted increasing attention for treating intractable diseases and improving tissue …