Ribosome-inactivating proteins from plants: A historical overview

A Bolognesi, M Bortolotti, S Maiello, MG Battelli… - Molecules, 2016 - mdpi.com
This review provides a historical overview of the research on plant ribosome-inactivating
proteins (RIPs), starting from the first studies at the end of eighteenth century involving the …

Antiviral activity of ribosome-inactivating proteins

L Citores, R Iglesias, JM Ferreras - Toxins, 2021 - mdpi.com
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22)
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …

Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review

J Mielgo-Ayuso, L Pietrantonio, A Viribay… - Nutrients, 2021 - mdpi.com
l-Carnitine (lC) and any of its forms (glycine-propionyl l-Carnitine (GPL-C) or l-Carnitine l-
tartrate (l-CLT)) has been frequently recommended as a supplement to improve sports …

Evolution and natural selection of ribosome-inactivating proteins in bacteria, fungi, and plants

J Liu, D Wen, X Song, P Su, J Lou, D Yao… - International Journal of …, 2023 - Elsevier
Ribosome-inactivating proteins (RIPs) are found in bacteria, fungi, and plants, with a wide
range of biological resistances such as anti-fungal, anti-viral, anti-insect, and anti-tumor …

How ricin damages the ribosome

P Grela, M Szajwaj, P Horbowicz-Drożdżal… - Toxins, 2019 - mdpi.com
Ricin belongs to the group of ribosome-inactivating proteins (RIPs), ie, toxins that have
evolved to provide particular species with an advantage over other competitors in nature …

Structural and functional characterization of the cytotoxic protein ledodin, an atypical ribosome‐inactivating protein from shiitake mushroom (Lentinula edodes)

L Citores, S Ragucci, R Russo, CC Gay… - Protein …, 2023 - Wiley Online Library
We have purified ledodin, a cytotoxic 22‐kDa protein from shiitake mushroom (Lentinula
edodes) consisting of a 197 amino acid chain. Ledodin possessed N‐glycosylase activity on …

Ribotoxic proteins, known as inhibitors of protein synthesis, from mushrooms and other fungi according to Endo's fragment detection

N Landi, HZF Hussain, PV Pedone, S Ragucci… - Toxins, 2022 - mdpi.com
rRNA N-glycosylases (EC 3.2. 2.22) remove a specific adenine (A4324, rat 28S rRNA) in the
sarcin ricin loop (SRL) involved into ribosome interaction with elongation factors, causing …

[HTML][HTML] Phylogeny and domain architecture of plant ribosome inactivating proteins

K Dougherty, KA Hudak - Phytochemistry, 2022 - Elsevier
Ribosome inactivating proteins (RIPs) are rRNA N-glycosylases (EC 3.2. 2.22) best known
for hydrolyzing an adenine base from the conserved sarcin/ricin loop of ribosomal RNA …

Ageritin, a Ribotoxin from Poplar Mushroom (Agrocybe aegerita) with Defensive and Antiproliferative Activities

L Citores, S Ragucci, JM Ferreras, A Di Maro… - ACS Chemical …, 2019 - ACS Publications
Ribotoxins make up a group of extracellular rRNA endoribonucleases produced by
ascomycetes that display cytotoxicity toward animal cells, having been proposed as …

Comparative genomic analysis of Babesia duncani responsible for human babesiosis

J Wang, K Chen, J Yang, S Zhang, Y Li, G Liu, J Luo… - BMC biology, 2022 - Springer
Background Human babesiosis, caused by parasites of the genus Babesia, is an emerging
and re-emerging tick-borne disease that is mainly transmitted by tick bites and infected …