Insights into brain microstructure from in vivo DW-MRS

M Palombo, N Shemesh, I Ronen, J Valette - Neuroimage, 2018 - Elsevier
Many developmental processes, such as plasticity and aging, or pathological processes
such as neurological diseases are characterized by modulations of specific cellular types …

In vivo brain GSH: MRS methods and clinical applications

F Bottino, M Lucignani, A Napolitano, F Dellepiane… - Antioxidants, 2021 - mdpi.com
Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …

Big GABA: Edited MR spectroscopy at 24 research sites

M Mikkelsen, PB Barker, PK Bhattacharyya, MK Brix… - Neuroimage, 2017 - Elsevier
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …

GABA—from inhibition to cognition: emerging concepts

T Schmidt-Wilcke, E Fuchs, K Funke… - The …, 2018 - journals.sagepub.com
Neural functioning and plasticity can be studied on different levels of organization and
complexity ranging from the molecular and synaptic level to neural circuitry of whole brain …

Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics

Y Koush, DL Rothman, KL Behar… - Journal of Cerebral …, 2022 - journals.sagepub.com
While functional MRI (fMRI) localizes brain activation and deactivation, functional MRS
(fMRS) provides insights into the underlying metabolic conditions. There is much interest in …

Metabolic underpinnings of activated and deactivated cortical areas in human brain

Y Koush, RA de Graaf, R Kupers… - Journal of Cerebral …, 2021 - journals.sagepub.com
Neuroimaging with functional MRI (fMRI) identifies activated and deactivated brain regions
in task-based paradigms. These patterns of (de) activation are altered in diseases …

Separate N‐acetyl aspartyl glutamate, N‐acetyl aspartate, aspartate, and glutamate quantification after pediatric mild traumatic brain injury in the acute phase

P Menshchikov, A Ivantsova… - Magnetic …, 2020 - Wiley Online Library
Purpose To separately measure N‐acetyl aspartul glutamate (NAAG), N‐acetyl aspartate
(NAA), aspartate (Asp), and glutamate (Glu) concentrations in white matter (WM) using J …

Accelerated J‐resolved 1H‐MRSI with limited and sparse sampling of (‐space

L Tang, Y Zhao, Y Li, R Guo, B Clifford… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To accelerate the acquisition of J‐resolved proton magnetic resonance
spectroscopic imaging (1H‐MRSI) data for high‐resolution mapping of brain metabolites …

Hadamard editing of glutathione and macromolecule‐suppressed GABA

G Oeltzschner, KL Chan, MG Saleh… - NMR in …, 2018 - Wiley Online Library
The primary inhibitory neurotransmitter γ‐aminobutyric acid (GABA) and the major
antioxidant glutathione (GSH) are compounds of high importance for the function and …

GABA levels in left and right sensorimotor cortex correlate across individuals

NAJ Puts, S Heba, AD Harris, CJ Evans, DJ McGonigle… - Biomedicines, 2018 - mdpi.com
Differences in γ-aminobutyric acid (GABA) levels measured with Magnetic Resonance
Spectroscopy have been shown to correlate with behavioral performance over a number of …