Advances in plant-derived C-glycosides: Phytochemistry, bioactivities, and biotechnological production

YQ Zhang, M Zhang, ZL Wang, X Qiao, M Ye - Biotechnology advances, 2022 - Elsevier
C-glycosides represent a large group of natural products with a CC bond between the
aglycone and the sugar moiety. They exhibit great structural diversity, wide natural …

Theoretical study on the glycosidic C–C bond cleavage of 3''-oxo-puerarin

J Choi, Y Kim, BE Eser, J Han - Scientific reports, 2023 - nature.com
Puerarin, daidzein C-glucoside, was known to be biotransformed to daidzein by human
intestinal bacteria, which is eventually converted to (S)-equol. The metabolic pathway of …

Specialized metabolites degradation by microorganisms

T Kumano - Bioscience, Biotechnology, and Biochemistry, 2024 - academic.oup.com
Secondary metabolites are specialized metabolic products synthesized by plants, insects,
and bacteria, some of which exhibit significant physiological activities against other …

[HTML][HTML] An alternative broad-specificity pathway for glycan breakdown in bacteria

SA Nasseri, AC Lazarski, IL Lemmer, CY Zhang… - Nature, 2024 - nature.com
The vast majority of glycosidases characterized to date follow one of the variations of the
'Koshland'mechanisms to hydrolyse glycosidic bonds through substitution reactions. Here …

Enzyme Machinery for Bacterial Glucoside Metabolism through a Conserved Non‐hydrolytic Pathway

K Kastner, J Bitter, M Pfeiffer, C Grininger… - Angewandte …, 2024 - Wiley Online Library
Flexible acquisition of substrates from nutrient pools is critical for microbes to prevail in
competitive environments. To acquire glucose from diverse glycoside and disaccharide …

Whole genome sequencing provides evidence for Bacillus velezensis SH-1471 as a beneficial rhizosphere bacterium in plants

Y Shen, Z Shi, J Zhao, M Li, J Tang, N Wang, Y Mo… - Scientific Reports, 2023 - nature.com
Bacillus is widely used in agriculture due to its diverse biological activities. We isolated a
Bacillus velezensis SH-1471 from the rhizosphere soil of healthy tobacco, which has broad …

[HTML][HTML] Structural and Functional Characterization of a Gene Cluster Responsible for Deglycosylation of C-glucosyl Flavonoids and Xanthonoids by Deinococcus …

V Furlanetto, DC Kalyani, A Kostelac, J Puc… - Journal of Molecular …, 2024 - Elsevier
Plant C-glycosylated aromatic polyketides are important for plant and animal health. These
are specialized metabolites that perform functions both within the plant, and in interaction …

Glycoside-metabolizing oxidoreductase D3dgpA from human gut bacterium

H Kim, HTN Mi, JH Ahn, JS Lee, BE Eser… - … in Bioengineering and …, 2024 - frontiersin.org
The Gfo/Idh/MocA family enzyme DgpA was known to catalyze the regiospecific oxidation of
puerarin to 3”-oxo-puerarin in the presence of 3-oxo-glucose. Here, we discovered that …

Functional metagenomics reveals an alternative, broad-specificity pathway for metabolism of carbohydrates in human gut commensal bacteria

SA Nasseri, AC Lazarski, IL Lemmer, CY Zhang… - bioRxiv, 2024 - biorxiv.org
The vast majority of the glycosidases characterised so far follow one of the variations of
the'Koshland'mechanisms to hydrolyse glycosidic bonds. Herein we describe a large-scale …

[HTML][HTML] Symbiotic and pathogenic factors in plant-microbe interaction: Structural basis of C-glycoside metabolism and lipoprotein transport in bacteria

V Furlanetto - 2023 - diva-portal.org
The communication between plants and bacteria involves a complex chemical signaling
network that mediates responses to various biotic and abiotic stresses, as well as …