Long noncoding RNAs in cancer metastasis
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …
multistep process that occurs through the acquisition of molecular and phenotypic changes …
Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …
contributing significantly to a diverse range of cellular processes, including apoptosis. One …
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
Accelerated glycolysis is the main metabolic change observed in cancer, but the underlying
molecular mechanisms and their role in cancer progression remain poorly understood …
molecular mechanisms and their role in cancer progression remain poorly understood …
Long non-coding RNA NEAT1 promotes bone metastasis of prostate cancer through N6-methyladenosine
Abstract Background N6-methyladenosine (m6A) is the most prevalent messenger RNA
modification in mammalian cells. However, the disease relevant function of m6A on specific …
modification in mammalian cells. However, the disease relevant function of m6A on specific …
Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness
VY Shin, J Chen, IWY Cheuk, MT Siu, CW Ho… - Cell death & …, 2019 - nature.com
Triple-negative breast cancer (TNBC) is a malignant subtype of breast cancer with the
absence of targeted therapy, resulting in poor prognosis in patients. Chemotherapy remains …
absence of targeted therapy, resulting in poor prognosis in patients. Chemotherapy remains …
The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
X Wang, Y Ji, P Feng, R Liu, G Li, J Zheng… - Advanced …, 2021 - Wiley Online Library
Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue
microenvironment. Currently, little is known about how the intrinsic regulators modulate …
microenvironment. Currently, little is known about how the intrinsic regulators modulate …
Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors
P Dong, Y Xiong, J Yue, SJB Hanley… - Frontiers in …, 2018 - frontiersin.org
The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …
LncSEA: a platform for long non-coding RNA related sets and enrichment analysis
J Chen, J Zhang, Y Gao, Y Li, C Feng… - Nucleic acids …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been proven to play important roles in
transcriptional processes and various biological functions. Establishing a comprehensive …
transcriptional processes and various biological functions. Establishing a comprehensive …
LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway
K Qiao, S Ning, L Wan, H Wu, Q Wang, X Zhang… - Journal of Experimental …, 2019 - Springer
Background An increasing number of studies have shown that long noncoding RNAs
(lncRNAs) play essential roles in tumor initiation and progression. LncRNAs act as tumor …
(lncRNAs) play essential roles in tumor initiation and progression. LncRNAs act as tumor …
Insights into biological role of LncRNAs in epithelial-mesenchymal transition
Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …