To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions …

Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

Emerging data demonstrate homologous recombination (HR) defects in castration-resistant
prostate cancers, rendering these tumours sensitive to PARP inhibition. Here we …

Background & Aims Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the
predominant pediatric liver cancer, with limited therapeutic options for patients with …

Advanced prostate cancer (PCa) represents the fifth cause of cancer death worldwide.
Although survival has improved with second-generation androgen signaling and Parp …

Simple Summary This review discusses the synthesis and significance of fatty acids,
glycerophospholipids, and triacylglycerol in glioblastoma. The focus is on all enzymes …

Background Prostate cancer (PC) is a heterogenous multifocal disease ranging from
indolent to lethal states. For improved treatment-stratification, reliable approaches are …

Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …

Background & Aims Choline kinase α (CHKA) catalyzes conversion of choline to
phosphocholine and can contribute to carcinogenesis. Little is known about the role of …

Introduction: An altered metabolic regulation is involved in the development and progression
of different cancer types. As well as this, many genes associated with tumors are shown to …