Decoding sTREM2: its impact on Alzheimer's disease–a comprehensive review of mechanisms and implications
C Lin, Y Kong, Q Chen, J Zeng, X Pan… - Frontiers in Aging …, 2024 - frontiersin.org
Soluble Triggering Receptor Expressed on Myeloid Cells 2 (sTREM2) plays a crucial role in
the pathogenesis of Alzheimer's disease (AD). This review comprehensively examines …
the pathogenesis of Alzheimer's disease (AD). This review comprehensively examines …
Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients?
B Talavera Andújar, A Mary, C Venegas… - … science & technology, 2024 - ACS Publications
Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disease, which
is currently diagnosed via clinical symptoms and nonspecific biomarkers (such as Aβ1–42, t …
is currently diagnosed via clinical symptoms and nonspecific biomarkers (such as Aβ1–42, t …
Multi‐omics analyses highlight molecular differences between clinical and neuropathological diagnoses in Alzheimer's disease
Both clinical diagnosis and neuropathological diagnosis are commonly used in literature to
categorize individuals as Alzheimer's disease (AD) or non‐AD in omics analyses. Whether …
categorize individuals as Alzheimer's disease (AD) or non‐AD in omics analyses. Whether …
[HTML][HTML] Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins
SR Venati, VN Uversky - International Journal of Molecular Sciences, 2024 - mdpi.com
In this work, we explored the intrinsic disorder status of the three members of the synuclein
family of proteins—α-, β-, and γ-synucleins—and showed that although all three human …
family of proteins—α-, β-, and γ-synucleins—and showed that although all three human …
Metabolomic analysis of swainsonine poisoning in renal tubular epithelial cells
S Zhang, Y Zhang, H Yin, Y Liu, L Tang… - Frontiers in Veterinary …, 2024 - frontiersin.org
Locoweed is a poisonous plant widely present in grasslands around the world. Swainsonine
(SW), an indole alkaloid that, is the main toxic component of the locoweed. To understand …
(SW), an indole alkaloid that, is the main toxic component of the locoweed. To understand …
[PDF][PDF] Art and Destiny-Protein Chemistry of Disease
SGD Rüdiger - uu.nl
All vital biological processes involve proteins. To get a grip on our destiny at molecular level,
we need to master the art to understand, control and making proteins. This art is the …
we need to master the art to understand, control and making proteins. This art is the …