Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …

During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that modulates neuroplasticity in
the brain, and is one of the most widely investigated molecule in psychiatric disorders. The …

Precise genetic and epigenetic spatiotemporal regulation of gene expression is critical for
proper brain development, function and circuitry formation in the mammalian central nervous …

Background: Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that is involved in
the synaptic plasticity and survival of neurons. BDNF is believed to be involved in the …

Epigenetic signatures such as methylation of the monoamine oxidase A (MAOA) gene have
been found to be altered in panic disorder (PD). Hypothesizing temporal plasticity of …

As one of the most common psychiatric disorders, depression has been a major public
health problem. Growing evidence suggests that epigenetic modification is essential in …

Social anxiety disorder (SAD) is a commonly occurring and highly disabling disorder. The
neuropeptide oxytocin and its receptor (OXTR) have been implicated in social cognition and …